Self-excising designer proteins report isoform expression

Our proteome is much bigger than our genome because one gene produces several variants of proteins called protein isoforms, whose disbalance is implicated in many diseases. A new bioengineered reporter system now allows for the first time to follow protein isoform expression over time in live cells. The method helps to decipher the underlying regulatory mechanisms and enables screening for potential molecular interventions.

from Top Health News -- ScienceDaily https://ift.tt/3z2fLfy