Health & Fitness

A novel staging framework that assesses the progression of Huntington's disease (HD), similar to the way cancer is staged 0 to 4, has been developed by scientists; this 'significant' step paves the way for clinical trials of drugs in the earliest phase of disease.

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The cerebellum is essential for sensorimotor control but also contributes to higher cognitive functions including social behaviors. Researchers uncovered how dopamine in the cerebellum modulates social behaviors via its action on D2 receptors (D2R). These new findings pave the way to determine whether socially related psychiatric disorders are also associated with altered dopamine receptors expression in specific cerebellar cell types.

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Scientists have used Xenopus laevis tadpoles to tease out the genetic and biological mechanisms that enhance disease tolerance, and have identified drugs that can keep the tadpoles alive even in the presence of lethal bacteria. Many of the same mechanisms are also found in mammals, suggesting that humans and other animals could one day be treated for disease by increasing their tolerance to pathogens rather than killing the pathogens themselves.

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A common hormone disorder among women of reproductive age has been linked to an increased risk of adverse cardiovascular events and pregnancy outcomes at the time of birth, according to a new study.

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Scientists have identified the biochemical signals that control the emergence of the body pattern in the primate embryo. This will guide work to understand birth defects and pregnancy loss in humans.

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During recent decades, the rate of infertility among women in the United States has remained largely the same, according to researchers. Their new analysis of data collected from 1995 and 2019 found that infertility is more common among women who are older, who are non-Hispanic Black and who have less income or education, and women without access to sexual and reproductive health services.

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A new study shows targeting a protein in smooth muscle cells can block and decrease buildup of atherosclerotic plaque in mouse models, according to researchers.

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Researchers have developed a unique 3D printed system for harvesting stem cells from bioreactors.

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