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03/01/22

Neurons in the brain coexist with and rely on many other cell types to function properly. Astrocytes, which take their name from their star shape, ensure the survival of neurons by feeding and detoxifying them with the help of a multifunctional protein, APOE. One of three forms of this protein, APOE4, significantly increases the risk of developing Alzheimer's disease, but the mechanisms at play are unknown.

from Top Health News -- ScienceDaily https://ift.tt/Lwym35X

A signature found in the cheek cells of mothers and fathers of preterm infants may help develop a test to determine whether a pregnancy may end too early. Such a test could help prevent premature births and the many resulting health impacts on infants by alerting medical providers to the need for early intervention measures. In a proof of concept study, researchers documented more than 100 epigenetic biomarkers in mothers of preterm babies that were distinct from mothers of babies carried to term. Fathers had fewer biomarkers but enough to indicate a likely paternal role in preterm birth. They also found that the preterm female babies carried more than 100 of these biomarkers, indicating the propensity to have a preterm baby may be passed down.

from Top Health News -- ScienceDaily https://ift.tt/5Hr2hpf

Doing less exercise could deactivate a vital protein in the body, causing further inactivity and making exercise more difficult, new research suggests.  Deactivating the Piezo1 protein, a blood flow sensor, reduces the density of capillaries carrying blood to the muscles.  This restricted blood flow means activity becomes more difficult and can lead to a reduction in how much exercise is possible. This helps to explain the biology of why exercise becomes harder the less you do.

from Top Health News -- ScienceDaily https://ift.tt/6bHaCRy

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