Health & Fitness

Taste receptors for bitter substances are not only found on the tongue but also on cells outside the oral cavity. As a new study now shows, extraoral bitter taste receptors could also serve as endogenous sensors for bile acids. This discovery suggests that, in addition to food components, endogenous substances may have influenced the evolution of bitter taste receptors. Furthermore, the study provides new approaches to explore the health effects of food constituents in which extraoral bitter taste receptors are involved.

from Top Health News -- ScienceDaily https://ift.tt/9kLSP0f

The study combines a deep learning model with CRISPR screens to control the expression of human genes in different ways -- such as flicking a light switch to shut them off completely or by using a dimmer knob to partially turn down their activity. These precise gene controls could be used to develop new CRISPR-based therapies.

from Top Health News -- ScienceDaily https://ift.tt/ief8mn4

Adenosine base editing restarted fetal hemoglobin expression in cells from patients with sickle cell disease.

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Pregnant women may be better supported by trained dietitians to control weight gain during pregnancy, according to a new analysis of almost 100 studies.

from Top Health News -- ScienceDaily https://ift.tt/gHJtF4K

A team of scientists from around the globe has gained high-res structural insights into a key bacterial enzyme, which may help chemists design new drugs to inhibit it and thus suppress disease-causing bacteria. Their work is important as fears continue to grow around rising rates of antibiotic resistance.

from Top Health News -- ScienceDaily https://ift.tt/4FoaLZP

Breast cancer is the most commonly diagnosed cancer amongst women in Australia. Here, Body+Soul speaks with Martine Dimes, who was diagnosed with breast cancer and the BRCA2 gene at just 29 years old. 

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