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10/10/22

Clinical AI tools hold the promise to transform the practice of medicine, but lack of transparency in some tools is an ongoing challenge. One way to demystify black-box AI reasoning is the use of heat maps that 'explain' how an AI tool made a diagnosis based on a specific clinical image. A new study suggests that heat maps underperform human clinicians, are not ready for prime time and should be refined before wider adoption in clinical practice.

from Top Health News -- ScienceDaily https://ift.tt/dGyRhED

A new advance overcomes present limitations in spatial transcriptomics with a DNA nanotechnology-driven method called 'Light-Seq.' Light-Seq allows researchers to 'geotag' the full repertoire of RNA sequences with unique DNA barcodes exclusive to a few cells of interest. These target cells are selected using light under a microscope via a fast and effective photocrosslinking process, and their RNAs made available to next-generation sequencing with the help of a new DNA nanotechnology-driven technique. This entire process can then be repeated for different cell populations in the same sample.

from Top Health News -- ScienceDaily https://ift.tt/XGmHrOY

New research based on data from 18 countries concludes that adults with better mental health are more likely to report having spent time playing in and around coastal and inland waters, such as rivers and lakes (also known collectively as blue spaces) as children. The finding was replicated in each of the countries studied.

from Top Health News -- ScienceDaily https://ift.tt/M7mwRNr

A new study provides the best evidence to date that scientists overall are most innovative and creative early in their careers. Findings showed that, on one important measure, the impact of biomedical scientists' published work drops by between one-half to two-thirds over the course of their careers.

from Top Health News -- ScienceDaily https://ift.tt/l0Girqo

Investigators have examined the microbiome of pancreatic tumors and identified particular microorganisms at single cell resolution that are associated with inflammation and with poor survival. According to the researchers, these microorganisms may be new targets for earlier diagnosis or treatment of pancreatic cancer, which is the fourth leading cause of cancer death for both men and women in the United States.

from Top Health News -- ScienceDaily https://ift.tt/K6Tgc1D

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