Health & Fitness

Engineers have found a way to dramatically improve the signal emitted by fluorescing nanosenors. The researchers showed they could implant sensors as deep as 5.5 centimeters in tissue and still get a strong signal. The advance allows the particles to be placed deeper within biological tissue, which could aid with cancer diagnosis or monitoring.

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One powerful way cancer cells defend against tumor-killing immune cells is to load up their cell surface with a protein known as PD-L1. Now a team of researchers has identified a method to degrade tumor cell-surface PD-L1, thereby making tumors susceptible to immune attack.

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Researchers describe biological mechanism that allows sleep to build relational memories -- associations between unrelated items.

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Researchers investigated genes connected to lifespan. Their research uncovered specific characteristics of these genes and revealed that two regulatory systems controlling gene expression -- circadian and pluripotency networks -- are critical to longevity. The findings have implications both in understanding how longevity evolves and in providing new targets to combat aging and age-related diseases.

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Breathing difficulties are the main cause of death following opioid use. In the UK, the number of adults entering treatment for opioid use was 140,863 in 2020/211 and opioid use remains a significant cause of premature death, contributing to 3,726 drug-related deaths last year. Opioid misuse causes death by supressing respiratory activity. New research points to a novel treatment for respiratory depression associated with opioid use that administers electrical pulses to the back of the neck, helping patients regain respiratory control following high dosage opioid use. This could offer an alternative to pharmacological treatments, which can cause withdrawal symptoms, heart problems and can negatively affect the central nervous system.

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Scientists have identified a new role for a protein complex at the center of a human genetic disorder called Bardet-Biedl syndrome, or BBS, for which there is currently no cure.

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