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09/22/20

From the beginning, researchers and scientists have been scrambling to find answers to a multitude of questions that affect patients with SARS-CoV-2. Scientists want to know how the virus infects human cells, how it is spread and what might be done to effectively treat a population that does not respond consistently.

In other words, there are some people who are either asymptomatic or have a mild illness and others who develop significant disease and die from the virus. Experts are asking what causes one person’s immune system to go out of control and not others’?

Interferon Plays a Critical Role Controlling Cytokines

The body uses type 1 interferon in response to many viral infections.1 As scientists have gotten a clearer understanding of how the virus affects the human immune system early in the disease, they have begun to theorize that interferons may be able to counter the process and prevent the development of severe illness.2

Interferons are a family of proteins produced by the immune system. Human-type interferons have also been commercially produced using recombinant DNA for treatment against viral infections, some cancers and multiple sclerosis.3 The objective is to change the immune system’s response to bacteria, cancer and viruses.

Natural interferon regulates the action of genetic material that secretes cellular proteins affecting growth.4,5 The theory is that building a stronger immune system will result in directing a strong defense against the virus and alleviating the cytokine storm.

In the 1990s interferon was used to treat hepatitis C. However, the cure rate was 30% or less and the side effects were significant, including psychiatric issues, liver problems and depression that sometimes led to suicide.6 Other side effects included fever, muscle aches, headaches and other flu-like symptoms.7

Dr. Anthony Fauci, director of NIH’s National Institute of Allergy and Infectious Diseases (NIAID), calls interferon “the best soldiers, as it were, of the innate immune system."8

Several trials are currently underway to evaluate the effectiveness of interferon in patients with COVID-19. These trials are the result of studies demonstrating that individuals with the worst cases of coronavirus have the weakest interferon response.

People With Severe Disease Have Impaired Interferon Response

One team conducted an immune analysis on 50 patients who presented in various stages of the disease. They found that those with severe and critical illness had an impaired interferon type 1 response.9 Another group from New York's Mount Sinai Hospital reported similar results in the journal Cell after studying the virus in infected cells in the lab, humans and ferrets.10 Their data showed low levels of interferon types 1 and 3 were associated with higher levels of chemokines.

One team used immune cells from the blood of individuals who had severe disease. Using mass cytometry, they assessed the immune response in patients with confirmed disease.11

As reported in the Washington Post, when the immune cells were challenged with bacteria and viruses the normal reaction of producing defense of molecules, including interferons, did not occur.12

British company Synairgen published In a July 2020 press release, British company Synairgen suggested results from a randomized clinical trial using inhaled interferons could be used to reduce the potential risk of developing severe disease.13 While these results are promising, it's important to note that the trial was limited and the results have not yet been peer-reviewed or published.

One month later, the NIAID announced they were sponsoring a clinical trial to test interferon in hospitalized patients.14 Scientists are currently recruiting for the trial and hope to evaluate data from 1,000 patients across 100 hospitals worldwide.

The patients in the study will be getting remdesivir, the antiviral approved by the FDA in spring 2020. Fauci commented on the combination:

“What you’re likely going to see, as more antivirals come along and then the monoclonal antibodies come along, will be a propensity to treating as early as you possibly can to prevent people from getting into the hospital.”

New Trial Couples Interferon With Remdesivir

Researchers are seeking answers as to whether interferon will give added value to the antiviral agent remdesivir. However, not all scientists think there may be positive results. Marta Gaglia is a microbiologist at Tufts University. She spoke with a reporter from The Washington Post, saying, “In principle, you could think, why don’t we just give it to everybody who has a viral infection ever. But in reality, it has proven less effective than we would like.”15

The results from remdesivir studies have not been positive, either. For instance, in one study published in the New England Journal of Medicine, the endpoint measurements were changed throughout the study.16 At the conclusion the single primary outcome measure was the number of days to recovery.17 All other criteria were moved to secondary outcome measurements.

This trial was also funded by the NIAID, which Fauci directs. Although the release generated enthusiasm, there were significant issues with the design and consequently the data, which I discussed in “The New COVID-19 Medication Isn't Backed by Results.”

A second study published in The Lancet concluded the drug was “not associated with statistically significant clinical benefits.”18 As the head of NIAID, Fauci has a vested interest in the development of the antiviral drug remdesivir. As it was, when he declared the results of the NEJM study to be “highly significant,”19 it suggests he should have also declared a conflict of interest in the use of the drug in the U.S.

When he was asked about the results of the study, which was stopped because of serious adverse events related to the drug, Fauci disregarded the evidence as “not adequate.”20 

Despite scientists' concerns over the veracity of the studies, the U.S. FDA issued an emergency use authorization for it May 1, 2020, which opened the door for compassionate use of the questionable drug.21

Retroviruses May Play a Role in COVID-19 Illness

One reason interferon may have a more positive result in the treatment of COVID-19 than they had with SARS or MERS is the potential that the SARS-CoV-2 virus is not completely responsible for the severe disease that affects a small percentage of the population.

In my interview with cellular and molecular biologist Judy Mikovits, Ph.D., she discusses the potential that the SARS-CoV-2 virus activates a retrovirus in the body. You can see the interview in my article, “Judy Mikovits Suggests Retroviruses Play a Role in COVID-19.”

The genetic code for a retrovirus is in ribonucleic acid (RNA), rather than in deoxyribonucleic acid (DNA). The virus uses an enzyme, reverse transcriptase, to transform the single strand of RNA into a double strand of DNA.22 The enzyme is in the host cell where the virus replicates and then spreads throughout the body. As Mikovits describes, the key to health is to keep these viruses silent.23

She believes her data show that the SARS-CoV-2 virus is not the cause of COVID-19 but rather the catalyst to its expression, as it activates a dormant XMRV retrovirus found in some people. XMRV stands for “xenotropic murine leukemia virus-related virus.” Xenotrophic refers to viruses that only replicate in cells other than those of the host species.

So, XMRVs are viruses that infect human cells yet are not human viruses.24 In my interview with her, Mikovits describes how many of the current vaccines may be contaminated with this retrovirus.

As some vaccine viruses are grown in contaminated animal cell cultures, the retroviruses are then transferred to the genetic material of the vaccine virus. This may well explain the varying effect the virus has, creating severe disease in some and asymptomatic or mild illness in others.

Consider These Options to Reduce the Severity of Disease

In addition to hand-washing and maintaining overall health, there are further strategies to consider. These are approaches you can use to help reduce the risk you'll get sick or reduce the severity of the illness if you do get sick, without depending on prescribed medications.

As I've written before, optimizing your vitamin D level is probably the easiest, least expensive and most beneficial strategy you can use to minimize your risk of COVID-19 and other infections. Unfortunately, there's a pandemic of vitamin D deficiency across all age groups.25,26,27

The report I wrote on vitamin D and the prevention of COVID-19 is a resource to help you understand the importance of optimizing it for healthy immune function. Evidence continues to be published demonstrating that vitamin D levels are an independent indicator of the risk for infection and hospitalization.28

There are many health experts who are getting significantly positive results using hydroxychloroquine in combination with zinc and azithromycin.29 However, you have access to a similar combination at home using quercetin and zinc. Quercetin is a natural antihistamine and anti-inflammatory30 that also functions as a zinc ionophore.31

In other words, it helps zinc to enter the cells and stem the tide of viral replication. This works not only in lung tissue but also in endothelial cells, which affect symptoms outside the pulmonary system.32

Zinc deficiencies are commonly found in older adults and in those who are obese, have diabetes or atherosclerosis.33 Likely not by coincidence, these are some of the same populations who have a higher risk of severe disease.34

I recently interviewed Dr. David Brownstein, who has a clinic outside of Detroit. He has successfully treated more than 100 patients with COVID-19 using nebulized hydrogen peroxide. You can see the interview in “How Nebulized Peroxide Helps Against Respiratory Infections.”

I first wrote about using nebulized hydrogen peroxide in April 2020 and since then have received some impressive testimonials of its effectiveness from friends and acquaintances who got severely ill and used it. Brownstein was an early adopter of both vitamin D optimization and nebulized peroxide.

He's been using nebulized peroxide in the clinical setting for 25 years and with each revision of his protocol, his patients have appeared to fare better than those before them. For a couple of months, Brownstein posted some video interviews with his patients in which they told their story.

However, he removed them after receiving a warning letter from the Federal Trade Commission in which they stated that since there was no established prevention, treatment or cure for COVID-19, any mention thereof is in violation of FTC law.



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Over the past few months, several investigations have highlighted the apparent influence of vitamin D in COVID-19 incidence, severity and mortality. Interestingly, recent genetic analysis has produced a novel hypothesis1 that helps explain the unusual disease progression of COVID-19.

The hypothesis,2 published in the journal eLife in July 2020, specifically identifies bradykinin, a blood pressure regulating chemical controlled by your renin-angiotensin system (RAS), as a primary culprit.

As reviewed in greater depth in "Bradykinin Hypothesis Explains COVID-19 Complexities," the lethality of COVID-19 may be due to the virus' ability to induce a bradykinin storm. The effects of the virus on your RAS also adds further support to the recommendation to optimize your vitamin D.

In fact, the researchers who came up with the novel bradykinin hypothesis stress the usefulness of vitamin D, as it plays an important role in the RAS system3,4,5,6 and suppresses the biosynthesis of a compound called renin (REN), thereby preventing a deadly bradykinin storm.

Conversely, if you are vitamin D deficient, your renin expression is stimulated, and based on the latest data, that may render you more prone to bradykinin storm. Other studies have also emerged in recent weeks, showing that raising patients' vitamin D levels has a dramatic and beneficial effect on COVID-19 outcomes.

Vitamin D Massively Reduces ICU Admissions

Among them is a pilot randomized clinical study7,8,9 published online August 29, 2020, which found hospitalized COVID-19 patients in Spain who were given supplemental calcifediol (a vitamin D3 analog also known as 25-hydroxycholecalciferol or 25-hydroxyvitamin D) in addition to standard of care — which included the use of hydroxychloroquine and azithromycin — had significantly lower intensive care unit admissions.

Patients in the vitamin D arm received 532 micrograms of calcifediol on the day of admission (equivalent to 106,400 IUs of vitamin D10) followed by 266 mcg on Days 3 and 7 (equivalent to 53,200 IUs11). After that, they received 266 mcg once a week until discharge, ICU admission or death.

Of those receiving calcifediol, only 2% required ICU admission, compared to 50% of those who did not get calcifediol. None of those given vitamin D supplementation died, and all were discharged without complications.

CDC Warns of Second Wave of COVID-19

In the video above, NBC News interviews Michael Osterholm, virologist and director of the Center for Infectious Disease Research and Policy at the University of Minnesota in Minneapolis, about the prospect of a second wave of COVID-19.

According to Osterholm, we likely have another 12 to 14 months of "a really hard road ahead of us." While Swedish statistics suggest the virus can and is dying off naturally, Osterholm believes cases will again rise as we move into fall and winter. Even if a vaccine does become available, it will take months to vaccinate the population, he notes.

Chief epidemiologist in charge of Sweden's coronavirus response, Anders Tegnell, has stated12 he does not believe Sweden will see a second wave with widespread contagion as the country is seeing a rapid decline in positive tests, indicating herd immunity is being achieved.13

That said, there are still open questions as to how long natural immunity might last.14 Some evidence points to months,15 while other data point to several years.16 Then there are the data suggesting herd immunity for COVID-19 occurs at much lower rates than normal.

As reported17 by Dr. James Hamblin in The Atlantic, infectious disease modeling by Gabriela Gomes, who specializes in nonlinear chaos dynamics, "selective depletion" of individuals susceptible to infection can rapidly reduce viral spread, and in the case of SARS-CoV-2, models suggest the threshold for herd immunity may occur below 20% of the population.

Yet other data18,19,20,21 suggest certain antibodies against other coronaviruses, such as the common cold, appear to provide some protection against SARS-CoV-2 as well, such that a majority of people may already have some level of immunity. So, there's a variety of "moving parts" that still need to be nailed down before we can come to any firm conclusions about future risks.

Vitamin D Versus Vaccine

While Osterholm22 and other health officials are still focused on getting people onboard with vaccination, both against influenza and COVID-19, no one at the federal level has as of yet addressed the elephant in the room, which is vitamin D deficiency and its impact on these infections.

Importantly, influenza vaccination has been shown23,24 — by the Department of Defense, no less — to increase the risk of subsequent coronavirus infections by 36%. If we are to follow the science, as Osterholm says, then we should not be so quick to overlook such findings.

Then, of course, there's the issue of whether a safe and effective COVID-19 vaccine is achievable. I've discussed the reasons for why I believe COVID-19 vaccines will fail in several previous articles. Vitamin D optimization, in contrast, is already known to be both safe and effective against not only influenza but also COVID-1925,26,27 and other respiratory infections.28

According to a 2017 systematic review29,30,31 published in The BMJ, vitamin D supplementation protected against acute respiratory tract infection. The number needed to treat (NNT) was 33, meaning 33 people had to take the supplement in order to prevent a single case of infection. Among those with severe vitamin D deficiency at baseline, the NNT was 4.

Meanwhile, a systematic review32 by the Cochrane Database of Systematic Reviews found that to prevent one case of influenza-like illness (defined33 by the World Health Organization as an acute respiratory infection), the NNT for inactivated vaccines was 40. To prevent a single case of confirmed influenza, the number needed to vaccinate (NNV) was 71.

Vitamin D Is an Important Modifier of COVID-19 Risk

In a November 1, 2020, commentary34 in the journal Metabolism Clinical and Experimental, JoAnn Manson and Shari Bassuk call for the elimination of vitamin D deficiency to effectively squelch the COVID-19 pandemic, noting that 23.3% of the total U.S. population have insufficient or deficient vitamin D levels, with people of color having disproportionately lower levels than non-Hispanic whites.

They list several types of studies showing vitamin D deficiency is "an important modifiable risk factor for COVID-19," including:35

Laboratory studies that demonstrate how vitamin D helps regulate immune function and the RAS, and modulate inflammatory responses to infection.

Ecologic studies showing populations with lower vitamin D levels or lower UVB radiation exposure have higher COVID-19 mortality,36,37,38 and the fact that people identified as being at greatest risk for COVID-19 hospitalization and death (people of color, the elderly, nursing home residents and those with comorbidities such as obesity, vascular conditions and chronic kidney disease) also have a higher risk of vitamin D deficiency.

Observational studies showing low vitamin D levels are associated with a greater risk of testing positive for SARS-CoV-2 and contracting acute respiratory infections.

According to a September 3, 2020, JAMA study,39,40 people who tested positive for SARS-CoV-2 were 1.77 times more likely to be deficient in vitamin D than those who tested negative for the virus — a statistically significant difference.

CTV News, which reported the JAMA results, also pointed out that:41 "The connection between vitamin D and other respiratory illnesses is well known.

According to the World Health Organization,42 vitamin D deficiency has been linked to pneumonia, tuberculosis and bronchiolitis," and that "research43 out of New Orleans found 100% of its sickest COVID-19 patients were deficient in vitamin D."

Randomized clinical trials showing vitamin D inhibits respiratory tract infections, especially in those with lower vitamin D levels at baseline.

Vitamin D Protects Your Lungs

A 2020 GrassrootsHealth study published in the journal Nutrients44 describes how vitamin D can reduce the risk of both influenza and SARS-CoV-2 infection by lowering the viral replication rate and reducing the pro-inflammatory cytokines that damage the lungs, leading to pneumonia.

Vitamin D also helps increase concentrations of anti-inflammatory cytokines that may help protect your lungs. The researchers recommended those at risk for COVID-19 take:

"10,000 IU/d of vitamin D3 for a few weeks to rapidly raise 25(OH)D concentrations, followed by 5000 IU/d. The goal should be to raise 25(OH)D concentrations above 40-60 ng/mL (100-150 nmol/L)."

Vitamin D and COVID-19 Comorbidities

Vitamin D may also help protect against COVID-19 by beneficially impacting many of the comorbidities associated with poor COVID-19 prognosis. In an August 2020 paper45 published in the NSF Journal, the authors review the "fatal relationship" between vitamin D deficiency in combination with comorbidities in COVID-19 patients, noting that:

" … low vitamin D status is common in Europe with the exception of the Scandinavian countries. The calculated COVID-19 mortality rate from 12 European countries shows a significant inverse correlation with the mean 25(OH)D plasma concentration.

This raises the question whether insufficient vitamin D supply has an influence on the course of COVID-19 disease? An analysis of the distribution of COVID-19 infections showed a correlation between geographical location (30–50° N+), mean temperature between 5–11 °C and low humidity.

In a retrospective cohort study (1,382 hospitalized patients) 326 died … The mortality of COVID-19 (cases/ million population) shows a clear dependence on latitude. Below latitude 35, mortality decreases markedly. Indeed, there are exceptions … however, the management of the pandemic may increase infection risk …

Older age and comorbidities are linked to an insufficient vitamin D supply. Over 60 years of age, a reduction in the synthesis of vitamin D in the skin becomes apparent, which further increases getting older …

Based on a meta-analysis including 30 studies with 53,000 COVID-19 patients, co-morbidities are risk factors for disease severity … Comorbidities and old age show a relationship with Renin-Angiotensin-Aldosteron-System (RAS), vitamin D status and COVID-19 infection."

How Vitamin D Helps Modulate SARS-CoV-2 Infection 

This brings us back to where I started. While this NSF Journal study does not make reference to bradykinin storm being part of the disease progression and lethality of COVID-19, it does review how vitamin D impacts your RAS (which regulates bradykinin), and how your RAS in turn plays a role in the progression of SARS-CoV-2 infection:46

"Infection with SARS-CoV-2 causes the virus spike protein to come into contact with ACE2 on the cell surface and thus to be transported into the cell. This endocytosis causes upregulation of a metallopeptidase (ADAM17), which releases ACE2 from the membrane, resulting in a loss of the counter regulatory activity to RAS.

As a result, proinflammatory cytokines are released extensively into the circulation. This leads to a series of vascular changes, especially in the case of preexisting lesions, which can promote further progression of cardiovascular pathologies.

SARS-CoV-2 not only reduces the ACE2 expression, but also leads to further limitation of the ACE2/Ang 1–7/Mas axis via ADAM17 activation, which in turn promotes the absorption of the virus. This results in an increase in Ang II, which further upregulates ADAM 17.

Thus a vicious circle is established turning into a constantly self-generating and progressive process. This process may contribute not only to lung damage (Acute respiratory distress syndrome - ARDS), but also to heart injury and vessels damage, observed in COVID-19 patients …

Several studies have shown increased plasma renin activity, higher Ang II concentrations and higher RAS activity as a consequence of low vitamin D status. The same applies to the decreasing Renin activity with increasing vitamin D levels. There is an inverse relationship between circulating 25(OH)D and renin, which is explained by the fact that vitamin D is a negative regulator of renin expression …"

The NSF Journal paper goes on to review the connections found between the RAS, vitamin D levels and a list of comorbidities shown to worsen COVID-19 outcomes, including high blood pressure, cardiovascular diseases, obesity, Type 2 diabetes and ARDS. It also reviews how vitamin D levels, RAS function and cytokine storms are interconnected. The authors state, in conclusion:47

"There is ample evidence that various non-communicable diseases (hypertension, diabetes, CVD, metabolic syndrome) are associated with low vitamin D plasma levels. These comorbidities, together with the often concomitant vitamin D deficiency, increase the risk of severe COVID-19 events.

Much more attention should be paid to the importance of vitamin D status for the development and course of the disease. Particularly in the methods used to control the pandemic (lockdown), the skin's natural vitamin D synthesis is reduced when people have few opportunities to be exposed to the sun.

The short half-lives of the vitamin therefore make an increasing vitamin D deficiency more likely. Specific dietary advice, moderate supplementation or fortified foods can help prevent this deficiency. In the event of hospitalization, the status should be urgently reviewed and, if possible, improved."

Summary

To summarize what the NSF and eLife journals tell us, when your vitamin D is low, your risk of COVID-19 complications and death increases because your renin expression is stimulated.

High renin increases both cytokines and bradykinin, placing you at risk for increased inflammation and oxidative stress resulting in both cytokine storm (as discussed in the NSF paper48) and bradykinin storm (as discussed in the eLife paper49).

Considering cytokine and/or bradykinin storms are key factors in COVID-19 mortality, it seems reasonable to conclude that anything that can help modulate and prevent these devastating storms would be of significant value. As of right now, the one thing we know can do that is vitamin D.

In addition to that, vitamin D lowers viral replication,50 boosts your overall immune function by modulating both innate and adaptive immune responses, reduces respiratory distress,51 improves overall lung function and helps produce surfactants in your lungs that aid in fluid clearance.52

Vitamin D also lowers your risk of comorbidities associated with poor COVID-19 prognosis, including obesity,53 Type 2 diabetes,54 high blood pressure55 and heart disease.56 In my view, there's every reason to believe vitamin D optimization will help lower your risk of COVID-19 complications and death, and no reason to dismiss this strategy. 

Optimize Your Vitamin D Level Now

My #StopCOVIDCold campaign seeks to raise awareness about the importance of vitamin D optimization to prevent a resurgence of COVID-19 hospitalizations and deaths.

As temperatures and humidity levels drop — two factors that influence the viability of the virus in air and on surfaces — it's quite likely we'll see a reemergence. But a surge in positive tests, by itself, should not be cause for panic.

Remember, a vast majority of so-called "cases," meaning positive tests, remain asymptomatic. I believe raising vitamin D levels among the general public can go a long way toward increasing the number of people who have no symptoms or only mild illness.

Now is the time to check your vitamin D level and start taking action to raise it if you're below 40 ng/mL. An easy and cost-effective way of measuring your vitamin D level is to order GrassrootsHealth's vitamin D testing kit and learn more about vitamin D and its impact on your health.



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Researchers have identified a potential drug candidate against enterovirus 71, a common cause of hand, foot and mouth disease in infants and young children. The compound of interest is a small molecule that binds to RNA, the virus's genetic material, and changes its 3-D shape in a way that stops the virus from multiplying without harming its human host. It's an antiviral strategy that could be used on other hard-to-treat diseases.

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New research overturns current scientific thinking on flu infection in pregnancy. The study helps explain why influenza can lead to life-threatening complications during pregnancy. The research also has implications for our understanding of how COVID-19 may be affecting the vascular system.

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As the National Vaccine Information Center (NVIC) prepares to host the three-day, three-night Fifth International Public Conference on Vaccination that will be broadcast online October 16 through 18, 2020, the theme we have chosen is “Protecting Health and Autonomy in the 21st Century,” because at no time in modern history has it been more important for all of us to take a stand and do just that.

This year, the orchestrated actions by governments around the world to restrict or eliminate civil liberties in response to the emergence of a new coronavirus has been unprecedented, and has had profound effects on the global economy and on the physical, mental and emotional health of billions of people.1

By mid-September 2020, there were about 29 million cases of the new Severe Acute Respiratory Syndrome (SARS-CoV-2) reported worldwide with about 925,000 associated deaths.

The United States, the third most populated country in the world at 330 million people, had recorded over 7 million cases and 198,000 deaths, with an estimated 598 deaths per million people, which is a higher death rate per million people than Sweden,2 where health officials have refused to order masking or lock down the country and allowed the population to acquire natural herd immunity to the virus.3,4

Overall COVID-19 Mortality Is Less Than 1%

According to the World Health Organization, the overall infection mortality rate for the new SARS coronavirus causing COVID-19 is about 0.6%,5 although some scientists say it is lower,6 while others estimate it can be as high as 1 to 2% in some parts of the world.7

Compared to Ebola with a 50% mortality rate8 or smallpox that killed 30%,9 or tuberculosis that still is a deadly disease killing 20% to 70%,10 or diphtheria at 5% to 10%,11 or the 1918 influenza pandemic with a 2.5% mortality rate,12 COVID-19 is near the bottom of the infectious diseases mortality scale with a less than 1% mortality rate in most countries.

Those at highest risk for complications and death include the elderly and those with one or more poor health conditions.13

The CDC recently reported that only 6% of COVID-19-related deaths were solely due to coronavirus infection and 94% of the people who died also had influenza or pneumonia; heart, lung or kidney disease; high blood pressure; diabetes, or another underlying poor health condition.14 Most studies suggest it is rare for children to suffer complications and die from COVID-19.15

But seven months after the World Health Organization (WHO)16 declared a coronavirus pandemic,17 and public health officials persuaded lawmakers to turn the world upside down, a lot of people are asking questions and so are doctors who disagree with each other about the facts. Questions like:

Where did the new respiratory virus come from?

The most popular narratives about the mutated coronavirus is that it either jumped out of a bat or another animal in a Chinese wet food market18,19 or escaped out of a biohazard lab in 2019,20,21 but scientists continue to argue about which scenario is more likely.22 And this question:

If I wear a cloth facemask, does it really prevent me from getting infected with or transmitting COVID-19?

There is an ongoing debate in the medical community about whether it is a good idea for all healthy children and adults to wear cloth masks when they leave their home.23 In March 2020, the U.S. Surgeon General ordered the American public to stop buying and wearing masks because “they are not effective in preventing general public from catching coronavirus”24 and “actually can increase the spread of coronavirus," which was the position of the World Health Organization.25

But in April, the CDC walked back its “do not mask” order and urged all healthy Americans to voluntarily wear homemade cloth face coverings when entering public spaces.26

In June, the WHO was continuing to say that, “At the present time, the widespread use of masks everywhere is not supported by high-quality scientific evidence, and there are potential benefits and harms to consider … Masks on their own will not protect you from COVID-19.”27

But by June, a number of state Governors and local governments had mandated facemask wearing and an epidemic of mask shaming had begun,28,29 which led to public protests against masking mandates.30 In August, the CDC doubled down and expanded face masking directives to include all children over the age of 2,31 while the WHO warned that children under the age of 6 should not wear masks but children over age 12 should.32

So, confusion reigns. While some scientists are saying that if all healthy people are forced to wear face masks it will not stop the coronavirus pandemic and gives a dangerous and false illusion of safety,33 other scientists are demonizing the refusers, alleging that people refusing to mask up are “sociopathic” and have lower levels of empathy.34

About 30 U.S. states require masking for young children and adults who enter public spaces,35 and some states are leveling steep fines of up to $1,000 or threatening jail time for anyone who fails to comply.36

Washington state has made not wearing a mask in public a misdemeanor crime37 and central Texas officials say they wish they could put people in prison for refusing to wear a mask.38 More than 50 countries in the world now require people to cover their faces when they leave home and some do fine and imprison people who go outside without wearing a mask.39

So, what about getting tested for COVID-19? The CDC says that people should get tested if they have COVID-19 symptoms or have been in contact with someone who has been diagnosed with the infection. There is also an antibody test to identify whether or not you have been infected in the past.40 But lab tests are not always reliable and people are asking this logical question:

If I get a lab test, will it accurately identify if I am currently infected or have been infected with COVID-19 in the past?

Unfortunately, it’s not clear how accurate any of the tests are, especially the antibody test for past infection because the presence of antibodies may not be the only way to measure immunity.41 The best guess is that the range of reported false negative results for the nasal swab test is between 2% and 50%, and the reported false negative results for the antibody blood test is up to 30%, depending upon when during or after the infection testing is performed.42

In July, a state lab in Connecticut admitted that 90 out of 144 people tested during a 30-day period — most of them nursing home residents — were inaccurately informed they were infected because of faulty, false positive lab tests.43 In August, 77 football players in the National Football League were given false positive test results when, after retesting, all the tests came back negative.44 People are also wondering what happens after they get COVID-19, asking this question:

If I recover from COVID-19 will I only get temporary immunity or will I have long-term immunity against reinfection?

The CDC says it is unknown how long immunity lasts or whether you can get the new coronavirus infection twice.45 However, last spring researchers found that out of 68 uninfected persons, the blood from one third of them contained helper T-cells that recognized the mutated SARS coronavirus.

They concluded the presence of these defensive helper T cells gives evidence for some residual immunity that may have been produced after common cold infections caused by other types of coronaviruses. This, the scientists said, “bodes well for the development of long-term protective immunity.”46

Another important study was published in the medical literature in August providing evidence for robust memory T cell immune responses in people who had recovered from even mild or asymptomatic cases of COVID-19, but had no detectable virus-specific antibodies.47

If people can have strong immune responses without symptoms and traditional antibody tests for proof of immunity don’t apply to COVID-19, public health officials may be underestimating the extent of population-level herd immunity that already exists in the U.S., where there have been more cases reported than anywhere else.

COVID-19 Public Health Laws a Public Relations Disaster

While doctors debate the science, it is becoming clearer that the response to the new coronavirus infection by government health officials has been a public relations disaster. The anxiety, fear and chaos created by regulations instituted by most governments after the declaration of a COVID-19 pandemic this year has torn the fabric of societies and affected public opinion about public health laws and vaccination.48

Now the people are being told that there is one — and only one — simple solution to resolving the crisis and getting back to normal: that is, the only way we can take off our masks and touch, hug, kiss or come close to each other again49,50,51,52,53,54 is for every person living in every country to get injected with one of the liability-free COVID-19 vaccines being fast tracked to market.55,56,57,58,59

In April, WHO officials at the United Nations launched a global initiative “to end the COVID-19 pandemic,” proclaiming that “no one is safe until everyone is safe.”60 By May, they were warning that if every person in the world doesn’t get injected with a COVID-19 vaccination, the virus “may never go away.”61 

The WHO,62 U.S. government63,64,65,66 and lawmakers in the European Union,67 along with wealthy and politically powerful nongovernmental organizations (NGOs) like the Gates Foundation,68,69,70 GAVI, the Vaccine Alliance,71 and Coalition for Epidemic Preparedness Innovations (CEPI)72 have given the pharmaceutical industry tens of billions of dollars to develop and fast-track experimental coronavirus vaccines to market and promote their universal use.73,74

At the same time, governments have given pharmaceutical companies a liability shield from lawsuits when COVID-19 vaccines injure or kill people.75,76 The hard sell is on, but a lot of people are NOT buying it.

People Are Rejecting the COVID-19 Vaccine Sales Pitch

Every poll taken this year has revealed that between 40% and 70% of people living in the U.S. and Europe do not plan to get a COVID-19 vaccine when it is licensed.77,78,79,80,81,82 Populations in developed countries are resisting the siren call for “solidarity,” as doubt about COVID-19 vaccines is becoming more common in developing counties, too.83

The pushback by a wary public has taken government officials by surprise. Apparently, they were banking that the economic and social deprivation, fear and chaos surrounding lockdowns would produce a bull market for experimental mRNA and DNA COVID-19 vaccines using technology that never has been licensed for humans.84

It is widely acknowledged now that a solid two-thirds of Americans or more will “just say no” to getting injected with a vaccine containing lab altered parts of a new coronavirus that scientists admit they still don’t know much about,85 vaccines that preliminary clinical trials have revealed may well cause more than just a few minor reactions.86 

A frustrated top U.S. health official has name-called Americans who refuse to go along with public health policies and laws, calling them “anti-science” and “anti-authority.”87,88 The truth is, people in this country and many others just don’t have confidence in the quality and quantity of the science or government health officials they are being told to trust.89

Angry that a growing number of people are reluctant to roll up their sleeves for a vaccine that is being rushed to market at “warp speed,” public health officials,90 billionaire Silicon Valley technocrats,91,92,93 doctors, attorneys and bioethics professors94,95,96,97,98 and politicians99 are beating the drum for swift enactment of “no exceptions” mandatory vaccination laws as soon as COVID-19 vaccines are licensed.100

Already, some cheerleaders at leading universities are banging that drum for approving and using experimental COVID-19 vaccines even before testing is done,101 and are calling for young, healthy people to be the first to get the vaccine because it is their “civic duty” to protect everyone else.102

They warn that “herd immunity may not be achieved if people refuse to take the coronavirus vaccine,”103,104 and say that, in order to keep society “safe,” laws must be passed to threaten and coerce you and your minor children to get vaccinated or face crippling social sanctions that will effectively take away your liberty and destroy your life.105

People in US and Other Nations Rise to Defend Freedom

This summer, huge public demonstrations defending freedom in Berlin,106 London,107 Paris108 and Copenhagen saw tens of thousands of citizens gather to protest masking109 and other oppressive coronavirus lockdown policies, which have severely restricted normal physical contact between people, caused widespread unemployment,110 and harmed their physical, mental and emotional health.111

Like in Europe, people living in Canada,112 Australia113,114 and New Zealand115 also are resisting months of social distancing policies that have eliminated fundamental human rights, such as freedom of speech and assembly.

The U.S. has seen similar but smaller public demonstrations opposing forced masking, social distancing and lockdown laws and defending freedom in Virginia,116 Pennsylvania,117 Wisconsin,118 Michigan,119 California120 and other states, as record numbers of Americans struggle with unemployment,121,122 the destruction of small middle class businesses,123 mortgage defaults124 and bankruptcy filings;125 steep increases in anxiety and depression,126,127 drug and alcohol addiction,128 child and spousal abuse,129 and divorce.130

Social Sanctions for Failure to Get Vaccinated May Align With Lockdown Sanctions

The punishing social sanctions being talked about if you refuse a COVID-19 vaccination are likely to be enforced using government-operated electronic tracking systems linked to digital “immunity passports” that require you to “prove” you are immune to the new SARS coronavirus before you are allowed to work in an office building or enter other public spaces.131,132,133,134

These social sanctions for failure to vaccinate may closely resemble the types of social interaction restrictions enforced in the U.S. and other countries over the past year.

In the U.S., most public health laws, including vaccine laws, are enacted by the states,135 while the federal government makes vaccine use recommendations and can mandate vaccines for people crossing national or state borders. Local city and county governments also can impose their own public health regulations.136 That is why some states and cities have seen very restrictive COVID-19 pandemic masking137 and lockdown regulations138 and others have been more open.139

So, whether or not you will be punished for refusing to get a COVID-19 shot next year primarily will be determined by your state’s governor and the representatives who have been elected to make laws in your state capitol.140

Depending upon where you live and the political philosophy of the majority of representatives in your state legislature, after the COVID-19 vaccine is licensed by the federal Food and Drug Administration (FDA) and recommended by the CDC for use by all children and adults,141 if you refuse to get a COVID-19 shot, you could be blocked from:142

Being employed and going to work in an office

Getting an education

Obtaining a driver’s license or passport

Boarding a train or other public transportation

Attending a sports game or concert

Entering a store, restaurant, bar, coffee shop or nail salon

Booking an appointment with a doctor

And you could be prohibited from checking into a hospital for surgery, or visiting a family member in a nursing home, or blocked from obtaining private health insurance and Medicaid or Medicare.

In other words, if you refuse to get a coronavirus vaccination, you could be subjected to the kinds of punitive social sanctions I have been predicting and publicly warned about since 1997,143,144,145,146 sanctions that are already being applied to Americans who decline to get or give their children dozens of doses of CDC “recommended” liability-free vaccines147 and already are being denied an education, medical care and employment.148,149

Broken Promises Leads to Broken Trust

Doctors and public health officials wondering why people don’t trust what they say about infectious diseases and vaccination, including coronavirus and COVID-19 vaccines, only have to look in the mirror to answer the question.

Since 1982, parents of vaccine injured children have been begging doctors to do the kind of science that will explain why so many highly-vaccinated children, who don’t get measles or chicken pox anymore, are stuck on sick and suffering with brain and autoimmune disorders that never go away.150 For four decades, we have been asking doctors and government health officials to stop sweeping casualties of inhumane one-size-fits all vaccine policies, under the rug.151

What we get from medical professors in universities receiving lots of money from the government and pharmaceutical companies, and from doctors developing vaccines, and from public health officials pushing “no exceptions” vaccination policies are threats, name-calling, bullying and punishment if we try to exercise informed consent to vaccination.152,153,154 There is no other word for it but abuse.

They order us to obey them but refuse to take responsibility for what happens when we obey the orders they give. They expect us to trust them and refuse to care about the victims of vaccination when the benefits do not outweigh the risks.

Instead, they act to protect the power and profit-making of their business partners: the pharmaceutical industry, medical trade associations, multinational media corporations and Silicon Valley billionaires, and leave vaccine victims to take care of themselves. What’s trust got to do with it?

Broken trust has everything to do with why the majority of people in the U.S. and Europe do not want to roll the dice and find out whether the odds of surviving a COVID-19 vaccination are in their favor.

It is during this extraordinary time of great challenge and opportunity that NVIC is sponsoring the Fifth International Public Conference on Vaccination. Our conference will create an expanded base of knowledge about vaccine science, policy, law and ethics brought to you by more than 40 distinguished speakers, who will empower you with information you need to become an effective vaccine freedom advocate.

Go to NVIC.org and register today for this historic conference celebrating freedom of thought, speech and conscience and gain permanent online access to this valuable video library of information. It’s your health, your family, your choice. And our mission continues: No forced vaccination, not in America.



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The Health and Human Services' Operation Warp Speed pledges to deliver 300 million doses of a COVID-19 vaccine by 2021.1 However, developing a safe and effective vaccine normally takes years and begins with animal studies. Given the urgency of the COVID-19 pandemic, vaccine makers are rushing into human clinical tests and circumventing lengthy animal trials.

Such fast-tracked vaccines pose unknown risks to humans, which are magnified because governments are granting COVID-19 vaccine makers immunity from liability for all vaccine injuries and deaths that occur after the vaccines are recommended (or mandated) by public health officials.2

In August, AstraZeneca announced that most countries it expects to supply with COVID-19 vaccine will grant the pharmaceutical company liability protection when people are harmed by the new vaccine.

In the U.S., vaccine makers already have something of a "free pass" when it comes to vaccine injury liability and lawsuits through the National Childhood Vaccine Injury Act of 19863 and the Public Readiness and Emergency Preparedness (PREP) Act, passed in 2005 (more on those later.)4

The main concern is that the combination of COVID-19 vaccines being fast-tracked to market at "warp speed" with minimal testing, together with blanket liability protection for Pharma for injuries their products cause, is a public health nightmare waiting to happen.

Vaccine Makers Already Enjoy Protection in the US

When the National Childhood Vaccine Injury Act became law in 1986, it gave vaccine manufacturers partial liability protection from lawsuits and did not protect doctors or other vaccine providers for vaccine injury malpractice claims.

The 1986 Act established a federal no-fault vaccine injury compensation program (VICP) as an administrative alternative to a lawsuit for injuries caused by vaccines recommended by the CDC for children.

Contested vaccine injury claims are adjudicated by U.S. Court of Federal Claims in Washington, D.C., and there is a Trust Fund out of which claims are paid, sparing insurance companies representing vaccine makers and vaccine providers from costly payouts for vaccine injuries and deaths.5

According to Legal Talk Network, the purpose for the 1986 Act was to induce vaccine makers wary of costly vaccine injury lawsuits to stay in the vaccine manufacturing business and create and market vaccines with impunity and no fear of being sued.6

Unfortunately, the bottom line is that, today, if you receive an FDA-licensed and state-mandated vaccine that injures or kills you or your child, the vaccine maker and the health care practitioner who administered the vaccine are protected from being sued in civil court. But the story behind it goes far deeper.

The Act Admits That Vaccines Can and Do Cause Injury, Death

Barbara Loe Fisher, co-founder and president of the National Vaccine Information Center, worked closely with Congress7 for years before the 1986 Act became law. In the historic federal legislation that was characterized by the pharmaceutical and medical care industries as badly needed "tort reform," the U.S. government acknowledged for the first time that:8

1. Federally licensed and recommended vaccines mandated by states for children to attend school can and do cause injury and death

2. Vaccine safety should be a priority for health agencies, vaccine manufacturers, doctors and other vaccine administrators

3. Individuals injured by government recommended and mandated childhood vaccines should have access to a federal vaccine injury compensation program administrative alternative to filing a vaccine injury lawsuit in civil court. Furthermore, they should have access to the civil court system in cases where:

Federal compensation is denied or is inadequate

There is evidence a pediatrician or other vaccine administrator negligently administered a vaccine

A vaccine manufacturer engaged in criminal fraud or negligence

A vaccine manufacturer could have made a vaccine less harmful (design defect)

New Laws and Rulings Chip Away at the Act

According to NVIC, the safety and compensation provisions in the 1986 law have been chipped away to the point that the law has been fatally compromised. At the time the Act was passed:9

"Although vaccine product liability for manufacturers was restricted, it was not completely eliminated, and manufacturers continued to be liable for design defect.

In 1987, medical trade organizations successfully lobbied for inclusion of a one-sentence amendment in an Omnibus funding bill that broadened liability protection for pediatricians and other vaccine administrators, but did not broaden liability protection for vaccine manufacturers when there was evidence the company could have made a vaccine less harmful."10,11

The erosion of the law continued in 2011 when, in a split decision, the U.S. Supreme Court:

"… blocked the legal right of vaccine injured persons to hold drug companies liable for design defect and failing to improve an FDA licensed vaccine to make it less harmful.12 This means that, today, even if a drug company could have improved a government licensed and mandated vaccine to make it less reactive, a vaccine injured person cannot sue the company in a civil court in front of a jury of peers."

According to NVIC:13

"Neglect and lack of congressional oversight on the Act for more than 30 years has enabled DHHS and the Department of Justice to turn what was supposed to be a non-adversarial, expedited, less expensive, fairer and more predictable federal vaccine injury compensation program, which Congress promised parents in 1986, into a highly adversarial, lengthy, traumatic and unpredictable imitation of a lawsuit in front of a one-person jury."

With No Liability Vaccine Makers Race to Make Vaccines

With the threat of vaccine injury lawsuits removed, more pharmaceutical companies have entered the lucrative vaccine business. For the past three decades, the global vaccine industry has been busy creating hundreds of new experimental vaccines, pushing for some of them to be fast-tracked, even before the recent push for a COVID-19 vaccine.

It doesn't matter how sloppy their work is or whether there is a lack of safety testing because, with no liability, there is no reason for safety testing, Robert Kennedy Jr., founder and chairman of the board of directors of the Children's Health Defense, says in a video.14

Their biggest cost, "paying liability at the back end," is not there, Kennedy says. "There's no reason to make [vaccines] safe because nobody can sue [them] … there's no consequence of giving you a really dangerous vaccine … it's a goldmine. If you can get a vaccine on the CDC schedule, it's worth a billion dollars a year typically to your company."

Moreover, the public has no redress against potential harm from the vaccine companies. "You cannot sue them for redress," says Kennedy. "There's no discovery; there's no depositions; there's no medical malpractice; there's no class actions."

The PREP Act Also Protects Vaccine Makers

In 2005, the Public Readiness and Emergency Preparedness Act (PREP Act) was passed as part of Bioshield legislation addressing potential bioterrorism threats after 9/11. The PREP Act shields vaccine makers from lawsuits for injuries caused by vaccines created and used during a declared public health emergency (such as the COVID-19 pandemic).

According to the Department of Health and Human Services, the PREP Act provides immunity from "claims of loss caused" by countermeasures or treatment of:15

"… diseases, threats and conditions determined by the Secretary to constitute a present, or credible risk of a future public health emergency to entities and individuals involved in the development, manufacture, testing, distribution, administration, and use of such countermeasures.

A PREP Act declaration is specifically for the purpose of providing immunity from liability, and is different from, and not dependent on, other emergency declarations."

Like the National Childhood Vaccine Injury Act, the Public Readiness and Emergency Preparedness Act of 2005, or Prep Act, facilitates the administration of potentially inadequately tested, risky vaccines and drugs by releasing drug manufacturers from all liability for covered "countermeasures."

Moreover, it gives the Secretary of HHS the power to detain, examine and quarantine indefinitely any individual thought to be infected with a communicable disease.

When the Act was passed in 2005, it paved the way for then HHS Sec. Kathleen Sebelius to impose quarantines and mandatory vaccinations if deemed necessary for the swine flu pandemic occurring at the time. Today, of course, the PREP Act allows those same scenarios as they relate to the COVID-19 pandemic.

AstraZeneca: Fast-Tracked Vaccines Need Liability Shield

Marketing of a COVID-19 vaccine is developing rapidly, especially in the U.K., where the government has signed vaccine supply pacts with AstraZeneca and Oxford, Pfizer, BioNTech, Valneva, Sanofi and GlaxoSmithKline.16 Yet, a recent article in Stat News asked "would vaccine manufacturers be willing to roll out vaccines on such a slight evidence base" without a liability shield? It's a good question that the article really didn't answer.17

Experts admit that "fast-tracking" to licensure an experimental vaccine like COVID-19 at "warp-speed" has never been done and is problematical for public safety. In an interview with Harvard Business School, Ken Frazier, chairman and CEO of Merck & Co., said:18

"I think when people tell the public that there's going to be a vaccine by the end of 2020, they do a grave disservice to the public … first of all, it takes a lot of time. I think the record for the fastest vaccine ever brought to market was Merck in the mumps vaccine. It took about four years. Our most recent vaccine for Ebola took five and a half years …

And here we [don't] even understand the virus itself or how the virus affects the immune system. We're starting there. We're starting with a spike protein as the antigen … we're hoping … to create a vaccine that we can study quickly that can be both safe and effective and … durable … if you're going to use a vaccine in billions of people, you better know what that vaccine does."

Officials at AstraZeneca, the U.K.'s second-largest drug maker, acknowledge that the risks of a hastily-marketed and tested vaccine necessitate a shield from risk which they have sought.

"This is a unique situation where we as a company simply cannot take the risk if in … four years the vaccine is showing side effects," Ruud Dobber, a senior AstraZeneca member, told Reuters.19 "In the contracts we have in place, we are asking for indemnification. For most countries it is acceptable to take that risk on their shoulders because it is in their national interest," he said.

A Grave Risk Barely Acknowledged by Big Vax

The history of vaccines against coronaviruses has not been encouraging — a paradoxical effect has been seen. Rather than fighting the infection, they can actually trigger what's known as paradoxical immune enhancement.

What this means is that, despite a robust antibody response when you're exposed to the actual virus, rather than protecting you, the vaccine actually enhances the virus' ability to make you sick or even kill you.

This paradoxical effect means that "the most hazardous hurdle for the inoculation is … challenging participants with wild COVID infection," says Kennedy.20 "Past attempts at developing COVID vaccines have always faltered at this stage as both humans and animals achieved robust antibody response, then sickened and died when exposed to the wild virus." He gives a chilling example:

"They tested it [a coronavirus vaccine] on about 35 children, and … the children developed a champion antibody response, robust, durable. It looked perfect, and then the children were exposed to the wild virus and they all became sick. Two of them died. They abandoned the vaccine. It was a big embarrassment to FDA and NIH."

Research published in the Journal of Translational Autoimmunity confirms that treatment with a vaccine may increase the risks associated with a wild type virus rather than protect against it. The researchers call the process pathogenic priming.21

"The problem, highlighted in two studies, became obvious following post-vaccination challenge with the SARS virus. [They] found that recombinant SARS spike-protein-based vaccines not only failed to provide protection from SARS-CoV infection [COVID-19], but also that the mice experienced increased immunopathology with eosinophilic infiltrates in their lungs.

Similarly [research] found that ferrets previously vaccinated against SARS-CoV also developed a strong inflammatory response in liver tissue (hepatitis). Both studies suspected a 'cellular immune response.'"

The pathogenic priming is consistent with other autoimmunity actions including the release of proinflammatory cytokines creating a storm, states the research. It has been seen in coronaviruses similar to COVID-19:22

"Similar to the SARS-CoV animal studies found that mice vaccinated against MERS-CoV (Middle East Respiratory Syndrome) develop[ed] exaggerated pulmonary immunopathology when challenged with the MERS virus following vaccination.

They reported that lung mononuclear infiltrates were observed in all groups after virus challenge, and that increased infiltrates that contained eosinophils and the eosinophil promoting IL-5 and IL-13 cytokines were observed only in the vaccinated animals."

Why would the recombinant vaccines create a greater risk for wild type viruses rather than protect against them? Because, according to the research, immunogenic peptides in viruses have "high local homologous matching"23 to human proteins, meaning they closely resemble each other allowing opportunistic invasion. The immunogenic peptides have:24

" … a large number of opportunities for expected disturbances in the immune system itself, targeting elements of MHC Class I and Class II antigen presentation, PD-1 signaling, cross-presentation of soluble exogenous antigens and the ER-Phagosome pathway."

The research concludes that such similarity between viruses and human proteins, called homology, likely explains the previous failure of SARS and MERS vaccines in the past and dooms a COVID-19 vaccine as well.

New COVID-19 Vaccine Technology Has Not Been Used Before

There is another risk with at least one of the new COVID-19 vaccine candidates, which uses a type of technology never before used in human vaccines, called mRNA.

According to Dr. Andrew Kaufman, a forensic psychiatrist who formerly served as clinical assistant professor of psychiatry at SUNY Upstate Medical University,25 RNA vaccines actually change the genetic makeup of our own cells in a form of gene therapy.26

While news outlets claim to have debunked27 Kaufman's evaluation, the fact remains that this is a type of vaccine that has never been licensed for use in humans before — so how do the debunkers know for certain that it doesn't change your DNA?

Conventional vaccines train your body to recognize and respond to the proteins of a particular virus by injecting a small amount of the actual viral protein into your body, thereby triggering an immune response and the development of antibodies. But, mRNA vaccines are designed to co-opt your body to force it to produce its own viral protein, which, theoretically your immune system should then attack.

As I said, the danger is that no previous vaccines have had your own cells produce the viral proteins responsible for producing immunity and no one can predict what will happen, especially for individuals genetically and epigenetically predisposed to developing autoimmune disorders.

What might go wrong when you turn your body into a viral protein factory making antibodies on a continual basis? Again, no one knows since no mRNA vaccines are on the market and their first users will be guinea pigs. But, according to researchers at the University of Pennsylvania and Duke University.28

"Potential safety concerns that are likely to be evaluated in future preclinical and clinical studies include local and systemic inflammation, the biodistribution and persistence of expressed immunogen, stimulation of auto-reactive antibodies and potential toxic effects of any non-native nucleotides and delivery system components."

When looking at other research the scientists also worried about blood clots and edema, and some of these effects, such as systemic inflammation and blood clots, resemble severe symptoms of COVID-19 itself. Since the changes work at the genetic level, could this vaccine technology create long-term or even generational effects in the human genome?

Brave New Vaccine Technology

To repeat, mRNA technology has never been approved for use in human vaccines that will function very differently from traditional vaccines. The mRNA technology is not like other viruses where a vaccine is inactivated or simply weakened. In a video Kaufman says:29

"They have to use a special technology. It is not like a regular vaccine where there's just a syringe with one needle and a liquid containing whatever is in the vaccine. This has three needles so the needle in the middle is the typical type that the material would flow through but the other two needles on either side are actually electrodes."

The electrodes generate an electric current inside of our cells called electroporation:

"… the electricity causes the cell membranes to create little holes called pores and then the genetic material can enter the cell through those pores whereas normally the cell membrane would be a barrier."

The bottom line is, Kaufman says, not only is the source of the genetic material found in the vaccine undetermined, but the brave new vaccines could be used for "all sorts of purposes that we may not know about."30

Extending protection from liability to vaccine-makers allows the irresponsible sale and marketing of vaccines that have been poorly tested and formulated because the manufacturers have "nothing to lose." If the mRNA vaccine technology found in many COVID-19 vaccines harms us and permanently alters our genes, unaccountable vaccine manufacturers will be totally off the hook.



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