Health & Fitness

Women with overactive bladder are frequently frustrated with treatment, which leads to discontinuation of therapy. Asynchronous telehealth visits keep women engaged in follow-up care, accelerates trials of different medications and reinforces behavioral changes. The women in this pilot study reported improvement in symptoms and high satisfaction with asynchronous visits.

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Researchers have successfully leveraged an FDA-approved drug to halt growth of tumors driven by mutations in the RAS gene, which are famously difficult to treat and account for about one in four cancer deaths.

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Metastatic cells form in a primary tumor and then break away from it, migrate to other organs, attach to them and form new tumors. This spread reduces patients' chances of recovery. Scientists have discovered some of the mechanisms by which these cells arise. This is due to cells that have narrowly escaped cell death (apoptosis) following a chemotherapeutic treatment. Those cells reprogram themselves to acquire metastatic skills. Thanks to this study, these cells - called PAME by the researchers - now appear as new therapeutic targets.

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Researchers have identified a potential way to battle the health effects of obesity and type 2 diabetes in women after discovering an important factor that could determine how their bodies use and store fat.

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A preclinical study led by a neuroscientist shows that dysregulated kappa-opioid receptors (KORs) in the brain's medial prefrontal cortex region (part of the frontal lobe) contribute to working memory deficits in severe alcohol dependence. The researchers discovered that an antagonist compound used to block KORs alleviated these working memory deficits and may help restore 'normal' executive function needed to make better decisions about alcohol consumption.

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Amyloid beta, a protein known to build-up in the brains of Alzheimer's patients, also helps skin cancer cells thrive when they spread to the brain, a new study finds.

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