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10/22/25

Texas A&M researchers found that in an aggressive kidney cancer, RNA builds “droplet hubs” that activate tumor genes. By creating a molecular switch to dissolve these hubs, they stopped cancer growth in lab and mouse tests. The work reveals how RNA can be hijacked to fuel disease, and how breaking its scaffolding could lead to new therapies for multiple pediatric cancers.

from Top Health News -- ScienceDaily https://ift.tt/jKaf7PU

Researchers have developed a DNA-based therapy that targets the PCSK9 gene to lower cholesterol naturally. Using polypurine hairpins, they increased cholesterol uptake by cells and reduced artery-clogging lipid levels. The results show dramatic drops in PCSK9 and cholesterol levels in animal models, pointing to a safer and more effective alternative to statins.

from Top Health News -- ScienceDaily https://ift.tt/KXrgYeI

Scientists have uncovered a toxic alliance between Aβ and fibrinogen that may explain how Alzheimer’s disease begins. The two proteins together create stubborn clots that damage blood vessels and spark inflammation in the brain. These effects appear even at very low concentrations and disrupt the blood-brain barrier, paving the way for neurodegeneration. The findings highlight a potential new therapeutic target for early intervention.

from Top Health News -- ScienceDaily https://ift.tt/dYWJRqS

A study found that daily vitamin D supplements helped slow telomere shortening—the cellular process linked to aging and disease. Researchers believe its anti-inflammatory effects may protect DNA. While results are promising, the ideal dose remains unclear, and experts stress that lifestyle choices still matter most for longevity.

from Top Health News -- ScienceDaily https://ift.tt/eOuUgEb

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