Health & Fitness

Scientists are uncovering a new possibility behind long COVID’s stubborn symptoms: hidden infections that awaken or emerge alongside SARS-CoV-2. Evidence is mounting that viruses like Epstein-Barr and even latent tuberculosis may flare up when COVID disrupts the immune system, creating lingering fatigue, brain fog, and other debilitating issues.

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Senescent “zombie” cells are linked to aging and multiple diseases, but spotting them in living tissue has been notoriously difficult. Researchers at Mayo Clinic have now taken an inventive leap by using aptamers—tiny, shape-shifting DNA molecules—to selectively tag these elusive cells. The project began as an offbeat conversation between two graduate students and quickly evolved into a collaborative, cross-lab effort that uncovered aptamers capable of binding to unique surface proteins on senescent cells.

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Researchers used a deep learning AI model to uncover the first imaging-based biomarker of chronic stress by measuring adrenal gland volume on routine CT scans. This new metric, the Adrenal Volume Index, correlates strongly with cortisol levels, allostatic load, perceived stress, and even long-term cardiovascular outcomes, including heart failure risk.

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