Health & Fitness

Scientists recently developed an efficient way to transplant pancreatic islets and demonstrated that the method can effectively reverse type 1 diabetes in nonhuman primates.

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Researchers have discovered a strong immunological effect of the molecule LecB -- and a way to prevent it.

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New research in mice shows bacteria hijack communication between nerve and immune cells in the meninges -- the protective layers that shield the brain from infection. The experiments detail step by step how bacteria activate pain receptors and initiate a signaling cascade that disables immune cells and culminates in bacterial invasion of the brain. The findings provide much-needed understanding into a critical window during the early stages of bacterial invasion when intervention could halt the spread of infection. The results point to therapeutic pathways for new treatments of bacterial meningitis, an often-fatal disease that can leave survivors with serious neurologic damage.

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A major new study reveals a 'traffic light' mechanism controlling genetic activity within cells -- a system which could potentially be targeted by cancer drugs already in development. The research describes how 'epigenetic' changes to the structure of DNA can act as a stop-go signal in determining whether a gene should be read. Unlike our genetic make-up, which is well understood, the world of epigenetics is still largely unexplored and referred to as the 'dark matter' of the genome.

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Decisions on cancer treatment could become better tailored to individual patients with the adoption of a new imaging method that maps the chemical makeup of a patient's tumor.

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A new study focused on defense veterans' mental health has found strong evidence that assistance dogs used in conjunction with traditional therapies provide the most effective treatment outcomes.

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Certain diseases, including Alzheimer's, are currently considered 'undruggable' because traditional small molecule drugs can't interfere with the proteins responsible for the illnesses. But a new technique that specifically targets and breaks apart certain proteins -- rather than just interfering with them -- may offer a pathway toward treatment. Researchers have now designed a compound that targets and breaks down a post-translationally modified protein closely associated with Alzheimer's disease.

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