Scientists have identified key changes to both chromosome structure and gene expression that affect stem cell function during aging. Using fruit flies, they found that these changes led to stem cell exhaustion, which prevents stem cells from multiplying. The findings provide the first evidence of an independent exhaustion signal and enhance our understanding of how the delicate balance between stem cell exhaustion and proliferation is disrupted in normal aging.
from Top Health News -- ScienceDaily https://ift.tt/9b7aTSx