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08/04/21

Eating a plant-centered diet during young adulthood is associated with a lower risk of heart disease in middle age, according to a long-term study with about 30 years of follow-up. A separate study with about 15 years of follow-up found that eating more plant-based foods that have been shown to lower cholesterol, called the 'Portfolio Diet', is associated with lower risk of cardiovascular disease in postmenopausal women.

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Researchers have announced successful results of a clinical trial for a commonly prescribed weight-loss drug called liraglutide. In adults who are overweight or have obesity combined with high cardiovascular risk, once-daily liraglutide combined with lifestyle interventions significantly lowered two types of fat that have been associated with risk to heart health: visceral fat and ectopic fat.

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Researchers found that a specific subtype of macrophages that originated from blood monocytes plays a key role in the hyper-inflammatory response in SARS-CoV-2 infected lungs, by performing single-cell RNA sequencing of bronchoalveolar lavage fluid cells. This study provides new insights for understanding dynamic changes in immune responses to COVID-19.

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A new study has revealed changes in healthy lung tissue which indicate preparation to receive metastases. The changes were identified in the area known as 'the micro-environment' of the tumor, and specifically in connective tissue known as fibroblasts.

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X-ray imaging is a fast and painless way for doctors to see inside a person. But radiation detectors, which go under the body part being imaged, are rigid panels that contain harmful heavy metals, such as lead and cadmium. Now, researchers report a proof-of-concept wearable X-ray detector prepared from nontoxic metal-organic frameworks (MOFs) layered between flexible plastic and gold electrodes for high-sensitivity sensing and imaging.

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In a proof-of-concept study, researchers have created a coating that can be applied to endotracheal tubes and release antimicrobial peptides that target infectious bacteria with specificity. The innovation could reduce upper-airway bacterial inflammation during intubation, a situation that can lead to chronic inflammation and a condition called subglottic stenosis, the narrowing of the airway by an accumulation of scar tissue.

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Adults infected with SARS-CoV-2 exhale different metabolites in their breath than uninfected people. Now, researchers have shown that children infected with SARS-CoV-2 also show breath metabolite changes, but they're largely different from the ones in adults. Someday, this information could be used to quickly and easily screen children for infection, the researchers say.

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