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01/18/23

Patients hospitalized with fractures typically receive an injectable blood thinner, low-molecular-weight heparin, to prevent life-threatening blood clots. A new clinical trial, however, found that inexpensive over-the-counter aspirin is just as effective.

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An investigational HIV vaccine regimen tested among men who have sex with men (MSM) and transgender people was safe but did not provide protection against HIV acquisition, an independent data and safety monitoring board (DSMB) has determined. The HPX3002/HVTN 706, or 'Mosaico,' Phase 3 clinical trial began in 2019 and involved 3,900 volunteers ages 18 to 60 years in Europe, North America and South America. Based on the DSMB's recommendation, the study will be discontinued.

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Timing from first meal to last meal was not associated with weight loss in a six-year study: Eating less overall and fewer large meals may be a more effective weight management strategy than restricting meals to a narrow time window, such as intermittent fasting, according to a study that analyzed the electronic health records of about 550 adults who were followed for six years. The time interval from first to last meal was not associated with weight change during the six-year study.

from Top Health News -- ScienceDaily https://ift.tt/GCTMHxS

Regulatory mechanisms of nutrient-dependent neuronal development can be explored at the molecular level with the Drosophila C4da neuron located in the fruit flies' larvae. The hyperarborization phenotype was not caused by low concentrations of amino acids but rather by a simultaneous deficiency in vitamins, metal ions, and cholesterol. Nutrient-dependent development of somatosensory neurons plays a role in optimizing a trade-off between searching for high-nutrient foods and escaping from noxious environmental threats.

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