Health & Fitness

Researchers have developed a way to analyze how individual immune cells react to the bacteria that cause tuberculosis. It could pave the way for new vaccine strategies and provide insights into fighting other infectious diseases.

from Top Health News -- ScienceDaily https://ift.tt/3hZBLS0

New hydrogels mimic intestines when lined with epithelial cells. A study demonstrated hydrogels in various stiffnesses are valuable for learning the dynamics of pathogens that cause diarrhea and other intestinal diseases.

from Top Health News -- ScienceDaily https://ift.tt/3y09OPq

An innovative testing platform that more closely mimics what cancer encounters in the body may allow for more precise, personalized therapies by enabling the rapid study of multiple therapeutic combinations against tumor cells. The platform uses a three-dimensional environment to more closely mirror a tumor microenvironment.

from Top Health News -- ScienceDaily https://ift.tt/2WcbmYD

After examining nearly the entire human genome for genetic changes that increase risk of aneurysm, researchers discovered a new change in the genetic code of a transcription factor.

from Top Health News -- ScienceDaily https://ift.tt/3xUb72h

Participation in elite adult rugby may be associated with changes in brain structure, according to a new study.

from Top Health News -- ScienceDaily https://ift.tt/3zp7WzV

Reduced mobility induced by the COVID-19 restrictions had only minor influence on particulate pollution levels, according to atmosphere studies in the Po Valley region of northern Italy. Eventually computer simulations indicated that the change in air quality led to an increase in secondary aerosol formation.

from Top Health News -- ScienceDaily https://ift.tt/3rFF4Rz

Researchers report the first structural confirmation that endogenous -- or self-made -- molecules can set off innate immunity in mammals via a pair of immune cell proteins called the TLR4-MD-2 receptor complex. The work has wide-ranging implications for finding ways to treat and possibly prevent autoimmune diseases such as multiple sclerosis and antiphospholipid syndrome.

from Top Health News -- ScienceDaily https://ift.tt/36WGehI

New research has uncovered the early assembly of gamma-secretase, a protein complex linked to numerous cellular processes including the development of Alzheimer's disease. In a first step, two dimeric subcomplexes are formed, which independently exit the ER and only afterwards assemble into a four-subunit complex. This 'buckle up' mechanism is thought to prevent premature assembly and activity.

from Top Health News -- ScienceDaily https://ift.tt/3iAMAZz

Scientists have successfully reversed age-related memory loss in mice and say their discovery could lead to the development of treatments to prevent memory loss in people as they age.

from Top Health News -- ScienceDaily https://ift.tt/3zuS4fr

Over the last few decades, neurodegenerative diseases became one of the top 10 global causes of death. Researchers worldwide are making a strong effort to understand neurodegenerative diseases pathogenesis, which is essential to develop efficient treatments against these incurable diseases. A team of researchers found out the implication of lysosomes in the spread of Parkinson's disease.

from Top Health News -- ScienceDaily https://ift.tt/3zrtOus

A new study shows that deep learning models trained on large sets of cancer genetic and tissue histology data can easily identify the institution that submitted the images.

from Top Health News -- ScienceDaily https://ift.tt/3kT7QMO

Findings could help pave the way for cancer therapies that target TAF12, potentially stopping transcription in cancer cells and helping decrease the growth of cancerous tumors.

from Top Health News -- ScienceDaily https://ift.tt/3rqGyyS

Researchers have found that omega-3 levels in blood erythrocytes are very good mortality risk predictors. The study used data from a long-term study group, the Framingham Offspring Cohort, which has been monitoring residents of this Massachusetts town, in the United States, since 1971 and concludes that, 'Having higher levels of these acids in the blood, as a result of regularly including oily fish in the diet, increases life expectancy by almost five years.'

from Top Health News -- ScienceDaily https://ift.tt/3iESj0u

Some antibiotics appear to be effective against a form of skin cancer known as melanoma. Researchers examined the effect of these antibiotics on patient-derived tumors in mice.

from Top Health News -- ScienceDaily https://ift.tt/3wSqdEc

New research represents one of the first studies to examine the effectiveness of targeted lionfish removals from both an ecological and a socio-economic perspective.

from Top Health News -- ScienceDaily https://ift.tt/3ruE4ze

With the application of a novel three-dimensional imaging technology, researchers have discovered that one portion of the autonomic nervous system in the liver undergoes severe degeneration in non-alcoholic fatty liver disease. The study, which is conducted in mice and human liver tissue, shows that the degeneration of nerves is correlated with the severity of liver pathology.

from Top Health News -- ScienceDaily https://ift.tt/3ztkPc7

Researchers have developed a tougher, safer bicycle helmet using a combination of materials. The new helmet prototype has higher energy absorption, reducing the amount of energy transferred to a cyclist's head in the event of an accident and likely lowering the chances of serious injury.

from Top Health News -- ScienceDaily https://ift.tt/3iCjLMn

Scientists have developed a 'nanobody' - a small fragment of a llama antibody - that is capable of chasing out human cytomegalovirus (HCMV) as it hides away from the immune system. This then enables immune cells to seek out and destroy this potentially deadly virus.

from Top Health News -- ScienceDaily https://ift.tt/3hW3H92

Researchers reported the development of a transferrable and integrative type I CRISPR-based platform that can efficiently edit the diverse clinical isolates of Pseudomonas aeruginosa, a superbug capable of infecting various tissues and organs and a major source of nosocomial infections. The technique can accelerate the identification of resistance determinants of multidrug resistant (MDR) pathogens and the development of novel anti-resistance strategies.

from Top Health News -- ScienceDaily https://ift.tt/36UOajy

More than 820 million people in the world don't have enough to eat, while climate change and increasing competition for land and water are further raising concerns about the future balance between food demand and supply. The results of a new study can be used to benchmark global food security projections and inform policy analysis and public debate on the future of food.

from Top Health News -- ScienceDaily https://ift.tt/3BuQQSZ

The standardized non-invasive clear cell likelihood score (ccLS) -- derived from MRI -- correlates with the growth rate of small renal masses (cT1a, <4 cm) and may help guide personalized management.

from Top Health News -- ScienceDaily https://ift.tt/3eMZfrf

Researchers have shown how the brain communicates to blood vessels when in need of energy, and how these blood vessels respond by relaxing or constricting to direct blood flow to specific brain regions.

from Top Health News -- ScienceDaily https://ift.tt/3y0moyb

Researchers have published evidence of the sustained benefits of an investigational antipsychotic treatment for people with dementia-related psychosis.

from Top Health News -- ScienceDaily https://ift.tt/3izXsHf