Health & Fitness

Scientists tracked the rise and fall of SARS-CoV-2 in the saliva and nasal cavities of people newly infected with the virus. The study was the first to follow acute COVID-19 infections over time through repeated sampling and to compare results from different testing methodologies.

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Investigators have devised a novel method for improving CAR T therapy through a drug combination and cellular engineering that improves the strength and durability of the tumor-killing effect of a CAR T directed against acute myeloid leukemia.

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CAR-T therapy, a form of immunotherapy that revs up T-cells to recognize and destroy cancer cells, has revolutionized the treatment of blood cancers, including certain leukemias, lymphomas, and most recently, multiple myeloma. However, Black and Hispanic people were largely absent from the major clinical trials that led to the U.S. Food and Drug Administration approval of CAR-T cell therapies.

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Researchers have been studying chronic traumatic encephalopathy (CTE) and while much has been learned, diagnosing the disease still needs to be done post-mortem on autopsied brains donated to a brain bank. One criticism of the research is that brain bank study results have a selection bias because they are based on a subset of players most affected by CTE, and therefore not representative of the population of football players. Now a novel study by researchers from BUSM and Boston University School of Public Health (BUSPH) provides further evidence suggesting a dose-response relationship between football and CTE even after adjusting for selection bias.

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Aspirin therapy, as opposed to statin use, for non-obstructive coronary artery disease does not reduce major cardiovascular events, according to a new study.

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Biomedical engineers have developed an artificial intelligence (AI) training strategy to capture images of mouse brain cells in action. The researchers say the AI system, in concert with specialized ultra-small microscopes, make it possible to find precisely where and when cells are activated during movement, learning and memory.

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A scientific team who studies a precancerous condition of the esophagus (called Barrett's esophagus or BE) are working to answer how to see genetic changes in cells before they turn cancerous. The team revealed that DNA changes in BE cells that presage esophageal cancer can be spotted years before cancer develops.

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