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01/08/20

Carpal tunnel, stiff shoulders, eye-strain headaches -- these are all well-known side effects of prolonged computer use. But what happens when you step away from the desktop and into virtual reality? A recent study assessed how some common virtual reality movements contribute to muscle strain and discomfort. It's an effort to ensure future user safety in this fast-growing technology that's used not only for gaming, but also increasingly for education and industrial training.

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A new study puts researchers within closer reach of vaccines that can protect infants against infections by overcoming a mother's antibodies, which are known to shut down immune defenses initiated by conventional vaccines. That hurdle largely explains why vaccinations for infectious diseases like influenza and measles not given until six to 12 months of age.

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The scientists pinpointed a small mRNA molecule used by TB bacteria to shut down key engines that drive our immune response. However, they also found a protein signal that removes this mRNA molecule and kick-starts the engines back into gear, providing hope for improved therapies in the future.

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A study of seven wastewater treatment plants in the Eastern United States points to two treatment methods -- granular activated carbon and ozonation -- as particularly promising. Each technique reduced the concentration of a number of pharmaceuticals, including certain antidepressants and antibiotics, in water by more than 95%, the scientists' analysis found.

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An isoelectric point is a common way to characterize viruses. However, it's not easy. To improve manufacturing for vaccines and gene therapy, a team uses surface charge to determine the isoelectric point of different viruses. Specifically, they use a single-particle method with atomic force microscopy (AFM).

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For the first time, researchers have mapped years of education and child malnutrition across all low- and middle-income countries at the level of individual districts. The findings include precision maps illuminating disparities within countries and regions often obscured by national-level analyses.

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New viruses which cause diseases often come from animals. Well-known examples of this are the Zika virus transmitted by mosquitoes, bird flu viruses, as well as the MERS virus which is associated with camels. In order to identify new viral diseases quickly and prevent possible epidemics, scientists are targeting their search at viruses in animals. In a current study, they have now discovered hundreds of novel viruses in insects.

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Researchers report that a type of biodegradable, lab-engineered nanoparticle they fashioned can successfully deliver a ''suicide gene'' to pediatric brain tumor cells implanted in the brains of mice. The poly(beta-amino ester) nanoparticles, known as PBAEs, were part of a treatment that also used a drug to kill the cells and prolong the test animals' survival.

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As a healthy heart ages, it becomes more susceptible to cardiovascular diseases. Though researchers have discovered that relaxin, an insulin-like hormone, suppresses atrial fibrillation (AF), inflammation, and fibrosis in aged rats, the underlying mechanisms of these benefits are still unknown. Researchers discuss how relaxin interacts with the body's signaling processes to produce a fundamental mechanism that may have great therapeutic potential.

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The goal of advertising is, of course, to catch your attention and sell you a product. But when it comes to health-related products, inaccuracies in advertising can be detrimental to your health.

Perhaps you’ve seen a Vitamin Water ad recently that touts the health benefits of Vitamin Water while seeming to discourage getting a flu shot as out of fashion. It originally appeared in 2011 but has mysteriously resurfaced online. The text of the ad states, “Flu shots are so last year,” and subheadings add “more vitamin C, more immunity, less snotty tissues.” The average customer seeing this ad could conclude that flu shots aren’t so great — in fact, that Vitamin Water is better for you than flu shots (and also better than getting the flu).

Vitamin Water won’t help against flu

I have to admit, the ad does catch your attention. But’s it’s an unfortunate and potentially dangerous approach for a number of reasons:

  • The flu killed an estimated 61,000 people in the US during the 2017–18 flu season (a record, according to the CDC) and up to 646,000 people worldwide; the flu shot could prevent many of these deaths.
  • The flu shot is recommended every year — that’s because the strains of the influenza virus change each year and the vaccination is modified accordingly.
  • There is a large and growing “anti-vax” campaign that falsely argues that the risks of vaccinations far outweigh their benefits; this not only poses a threat to those who forego vaccination and become sick with the flu, but also to those with whom infected persons come into contact.

I’m not the only one who took issue with this Vitamin Water campaign. The National Consumers League asked the Federal Trade Commission to ban the original ads, calling them “dangerously misleading.”

And then there’s the added sugar

Vitamin Water is one of many products whose name suggests health benefits or health advantages compared with its competitors, yet their nutritional content may be less healthy than you’d expect.

Read the label for Vitamin Water closely and you’ll see that it contains

  • 26 grams of sugar; that’s equivalent to more than six teaspoons of sugar, and more than half of the recommended allowance of carbs in a day
  • no protein or fiber
  • “ingredients sourced from genetically engineered crops (commonly known as GMOs).”

True, Vitamin Water has 25% of the daily recommendation for Vitamin A and 100% of Vitamins C, B6, and B12 — but the vast majority of people have no trouble getting plenty of these nutrients in the foods they eat.

Despite its name, there’s no obvious health advantage to getting vitamins along with the empty calories in Vitamin Water. Eat an orange instead if you’re seeking vitamin C — at least it has some fiber. And if you’re really worried you are not getting what you need from your diet, take a standard multivitamin — and see your doctor.

Of course, you could choose the zero-calorie version of Vitamin Water (and I do enjoy Vitamin Water Zero on occasion). But then you’re consuming the non-nutrient sweeteners, stevia and erythritol, the pros and cons of which we can debate another day.

Highly marketed supplements and diets versus proven treatments

For years, I’ve seen ads in my Sunday newspapers and elsewhere recommending all sorts of unproven treatments in lieu of well-studied, well-established, FDA-approved medications that have been proven to save lives. Examples include supplements and diets that claim to lower blood pressure or cure arthritis without medications. While diet is an important part of hypertension treatment, medications are typically prescribed for people who have already tried unsuccessfully to lower their blood pressure with nonmedication approaches. It’s potentially dangerous to suggest that you can stop blood pressure medications, as some glowing testimonials suggest — especially if you do so with no monitoring.

And I’ve seen many ads that proclaim, “Here’s a safe and all-natural cure for your condition that your doctor doesn’t want you to know about.” I don’t know any doctors who are keeping effective treatments secret. It’s an unfounded and cynical claim to suggest your doctor doesn’t have your best interests at heart. Meanwhile, the people using these sales tactics drive a wedge between doctors and patients in an effort to promote unproven health products.

The bottom line

You could argue that a reasonable person should know that the Vitamin Water ad is not advocating for anyone to skip their flu shot and that it’s just a way to promote their product. I disagree. Reasonable people are constantly bombarded with a torrent of misinformation. It can be hard to know which sources to believe. Downplaying the risk of skipping flu shots can have devastating consequences across a population.

Marketing works. But I think health-related marketing should be held to higher standards than ads for clothes, cars, or furniture. Advertisers should tread carefully when it comes to well-studied treatments proven to save lives. And until influenza is eliminated as a yearly health risk, it’s irresponsible and, yes, dangerous to liken flu shots to an out-of-fashion trend just to sell a sugary drink.

Follow me on Twitter @RobShmerling

The post Harvard Health Ad Watch: When marketing puts your health at risk appeared first on Harvard Health Blog.



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