Health & Fitness

Data scientists have created an artificial intelligence model that may more accurately predict which existing medicines, not currently classified as harmful, may in fact lead to congenital disabilities. The model, or 'knowledge graph,' also has the potential to predict the involvement of pre-clinical compounds that may harm the developing fetus. The study is the first known of its kind to use knowledge graphs to integrate various data types to investigate the causes of congenital disabilities.

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Many low-risk patients with a penicillin allergy were able to have their penicillin allergy label removed through a simple procedure known as 'direct oral challenge' as part of a world-first multicenter randomized control trial known as the Penicillin Allergy Clinical Decision Rule (PALACE) study.

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Researchers are using DNA 'origami' templates to control the way viruses are assembled. The global team behind the research developed a way to direct the assembly of virus capsids -- the protein shell of viruses -- at physiological conditions in a precise and programmable manner. Precise control over the size and shape of virus proteins would have advantages in the development of new vaccines and delivery systems.

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A recent study centers around the idea that various anti-inflammatory drugs could be effective treatments for Alzheimer's disease. This study focused on a protein known as p38. Many labs have been working with this protein as a potential target for drug development to treat Alzheimer's disease and other conditions with neuroinflammatory dysfunction.

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Pharmaceutical scientists and biologists are teaming up to make the next generation of lipid nanoparticles (LNPs) for drug delivery. Combining structural biology with cutting edge pharmaceutical science, the team is designing LNPs that can precisely deliver vaccines and therapeutics to target tissues while improving the product's shelf life and duration of action.

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ChatGPT's responses to people's healthcare-related queries are nearly indistinguishable from those provided by humans, a new study reveals, suggesting the potential for chatbots to be effective allies to healthcare providers' communications with patients.

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Giving patients with operable pancreatic cancers a three-pronged combination immunotherapy treatment consisting of the pancreatic cancer vaccine GVAX, the immune checkpoint therapy nivolumab and urelemab, an anti-CD137 agonist antibody treatment, is safe, it increases the amount of cancer-killing immune system T cells in the tumors and it appears effective when given two weeks prior to cancer-removal surgery, according to new research.

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Researchers have uncovered the role the thymus gland plays in creating and 'training' specialised anti-cancer white blood cells -- known as gamma delta T cells. This unsung organ produces these amazing cells after we are born -- so they can enter the body and start fighting off disease and infection.

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The United States is finally supporting its nation's women by approving their first ever non-prescription oral contraceptive pill.

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