Health & Fitness

COVID-19 convalescent plasma showed a likely benefit for patients early in the pandemic before remdesivir and corticosteroids were in use, according to results of a landmark study.

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Researchers have discovered a nanoparticle released from cells, called a 'supermere,' which contains enzymes, proteins and RNA associated with multiple cancers, cardiovascular disease, Alzheimer's disease and even COVID-19.

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New research sheds light on why a fecal transplant can benefit patients with dangerous recurrent C. difficile infections -- and suggests a way to improve patient outcomes.

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Using cannabis alongside other drugs may come with a significant risk of harmful drug-drug interactions, new research suggests. The researchers looked at cannabinoids--a group of substances found in the cannabis plant -- and their major metabolites found in cannabis users' blood and found that they interfere with two families of enzymes that help metabolize a wide range of drugs prescribed for a variety of conditions. As a result, either the drugs' positive effects might decrease or their negative effects might increase with too much building up in the body, causing unintended side effects such as toxicity or accidental overdose. While more research needs to be done, the authors said one early takeaway from these studies is that it's important to be careful when using cannabis with other prescription drugs.

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Embryonic development follows delicate stages: for everything to go well, many genes must coordinate their activity according to a very meticulous scheme and tempo. This precision mechanism sometimes fails, leading to more or less disabling malformations. By studying the Pitx1 gene, one of the genes involved in the construction of the lower limbs, a team has discovered how a small disturbance in the activation process of this gene is at the origin of clubfoot, a common foot malformation. Indeed, even a fully functional gene cannot act properly without one of its genetic switches.

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