Health & Fitness

Researchers have identified how cells in our brains work together to join up memories of separate experiences, allowing us to make educated guesses in everyday life. By studying both human and mouse brain activity, they report that this process happens in a region of the brain called the hippocampus.

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The scientists found that the more curved a toe spring is, the less power the foot inside the shoe has to exert when pushing off from the ground while walking. That means foot muscles are doing less work, and this, the researchers hypothesize, may have consequences such as less endurance and make people more susceptible to medical conditions like plantar fasciitis.

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For the first time, scientists have studied the early effects of time-restricted feeding on the daily periodic oscillations of metabolites and genes in muscle, and metabolites in blood. The findings find that time-restricted feeding does not influence the muscle's core clock, and opens the door to more research on how these observed changes improve health.

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For the first time, scientists solved the high-resolution structure of these compounds when they are actively bound to the 5-HT2A serotonin receptor on the surface of brain cells. This discovery is already leading to the exploration of more precise compounds that could eliminate hallucinations but still have strong therapeutic effects. Psilocybin - the psychedelic compound in mushrooms - has already been granted breakthrough status by the FDA to treat depression.

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For the first time, scientists have studied the early effects of time-restricted feeding on the daily periodic oscillations of metabolites and genes in muscle, and metabolites in blood. The findings find that time-restricted feeding does not influence the muscle's core clock, and opens the door to more research on how these observed changes improve health.

from Top Health News -- ScienceDaily https://ift.tt/3mz616r

Researchers have identified the protein GLT-1 as the neurotransmitter glutamate transporter in the brain that is related to cortical spreading depression, a pathological condition that underlies migraines. The researchers found that mice lacking GLT-1, but not other glutamate receptors, were more susceptible to cortical spreading depression than were controls. GLT-1 might therefore be a potential target for migraine therapy.

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When used to manage infections, the drug itraconazole is generally given at a single, fixed dose to all patients. But determining the correct dosage of the drug to help treat cancer isn't that simple, new research suggests.

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Researchers in Finland found a link between smoking and subarachnoid hemorrhage (SAH), a type of bleeding stroke, in a study of more than 16,000 pairs of twins over 42 years. The study found that bleeding in the brain can be explained to a greater degree by environmental risk factors, such as smoking, than by genetic influence.

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A new study deepens the understanding of the development of T cell, an important component of the immune system.

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Neuroscientists distinguish brain regions based on what they do, but now have a new way to overlay information about how they are built, too.

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Children who take oral steroids to treat asthma or autoimmune diseases have an increased risk of diabetes, high blood pressure, and blood clots, according to new researchers. The study is the first to quantify these complications of oral steroids in a nationwide population of children.

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A new study shows that single-dose and two-dose regimens of Vi-DT typhoid conjugate vaccine (TCV) are safe and immunogenic in children 6-23 months of age, a group with high rates of typhoid fever in resource-limited settings.

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Think spending time with your kids and spouse is the key to your happiness? You may actually be happier getting together with your friends, a new study finds.

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A research team has created a smart drug delivery system that reduces inflammation in damaged nervous tissues and may help treat spinal cord injuries and other neurological disorders. The system, which uses extremely thin biomaterials implanted in the body, also protects nerve fibers (axons) that connect nerve cells in injured neural tissues, according to a new study.

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Failures in a quality control system that protects protein-building fidelity in cells can lead to motor neuron degeneration and related diseases, according to a new study shows.

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Research has led to better understanding on how components of the body's immune system find intruding or damaged cells, which could lead to novel approaches to viral and cancer treatments.

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Scientists have now uncovered a key mechanism by which pancreatic function is maintained in response to a high-fat diet. A protein present in pancreatic insulin-producing cells protects them from damage under the stress induced by a high-fat diet. As the world increases its intake of high-fat foods and as type 2 diabetes incidence rises as a result, this protein could be a novel therapeutic target for type 2 diabetes mellitus.

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Scientists have now uncovered a key mechanism by which pancreatic function is maintained in response to a high-fat diet. A protein present in pancreatic insulin-producing cells protects them from damage under the stress induced by a high-fat diet. As the world increases its intake of high-fat foods and as type 2 diabetes incidence rises as a result, this protein could be a novel therapeutic target for type 2 diabetes mellitus.

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The negative effects of over-parenting on children are well documented, but less is known about why certain people become helicopter parents. A new study suggests perfectionism is one driver.

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Vaccines have curtailed the spread of several infectious diseases, such as smallpox, polio and measles. However, vaccines against some diseases, including HIV-1, influenza and malaria, don't work very well, and one reason could be the timing of antigen and adjuvant presentation to the immune system. Now, researchers have developed an injectable hydrogel that allows sustained release of vaccine components, increasing the potency, quality and duration of immune responses in mice.

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Using state-of-the-art robotics, a research team shows that animals' speed is fundamental for collective behavioral patterns, and that ultimately it is the faster individuals that have the strongest influence on group-level behavior.

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Trying to kickstart your health goals but struggling to make them stick? These best-selling weight loss books will change the way you view dieting and exercise, allowing you to succeed with ease.

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