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08/05/24

Investigators identified a chemokine/chemokine receptor mismatch for osteosarcoma (i.e., osteosarcomas secrete chemokines for which CAR T cells do not express receptors). The researchers modified CAR T cells targeting the osteosarcoma antigen B7-H3 to express CXCR2 or CXCR6 receptors, which recognize chemokines (CXCL8 or CXCL16) secreted by osteosarcoma.

from Top Health News -- ScienceDaily https://ift.tt/eECPTSo

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