Health & Fitness

Distinct immune 'signatures' in patients who develop adverse events while taking immunotherapy for cancer may help oncologists identify patients at risk and treat them early to prevent serious side effects, suggests a new study.

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Researchers have developed an innovative approach to epidemic modeling that could transform how scientists and policymakers predict the spread of infectious diseases. The study introduces a new framework that incorporates socioeconomic status (SES) factors -- such as income, education, and ethnicity -- into epidemic models. The study underscores an urgent need for more comprehensive epidemic modeling frameworks as societies continue to grapple with the lingering impacts of COVID-19 and prepare for future pandemics. By expanding beyond the conventional focus on age and context, this new approach opens the door to a more detailed understanding of disease transmission and offers a powerful tool for addressing health inequities.

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Alzheimer's disease may damage the brain in two distinct phases, based on new research using sophisticated brain mapping tools. According to researchers who discovered this new view, the first, early phase happens slowly and silently -- before people experience memory problems -- harming just a few vulnerable cell types. In contrast, the second, late phase causes damage that is more widely destructive and coincides with the appearance of symptoms and the rapid accumulation of plaques, tangles, and other Alzheimer's hallmarks.

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Preeclampsia is a life-threatening pregnancy complication marked by persistent high blood pressure that is even more serious when it occurs early in the first trimester. The exact cause of early-onset preeclampsia is unknown, and it is difficult to predict, prevent and diagnose. Now researchers report on six proteins that could be used as targets to diagnose and treat the condition.

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Use of a lifesaving drug to reverse opioid drug overdoses is growing, but not fast enough.

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Medicare could save up to 74% of the money lost from discarded Alzheimer's drug lecanemab by the simple introduction of a new vial size that would reduce the amount of unused medication that is thrown away. As it is, nearly 6% of the medication is discarded, costing Medicare $1,600 per patient per year.

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Higher levels of HDL-C -- known as the 'good cholesterol' -- have been shown to correlate with heightened risk for Alzheimer's disease. A new study might explain why.

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