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05/22/23

Researchers were able to identify changes in the accessibility (that is, the 'readability') of transposable elements. To do this, the researchers used an approach combining various sets of multiomics data, which characterize and quantify collections of biomolecules in cells or organisms. One was the transcriptome, which consists of all copies of RNA transcribed from DNA in the cell. The other was the epigenome, which is the collection of chemical changes to DNA that modify gene expression. An advantage of this multiomics approach is that they were able to identify families of transposable elements with changes in accessibility, which would have likely been missed by previous approaches.

from Top Health News -- ScienceDaily https://ift.tt/RP73nDp

Ants' brains are amazingly sophisticated organs that enable them to coordinate complex behavior patterns such as the organization of colonies. Now, researchers have developed a method that allows them to study ants' brain chemistry and gain insights into the insects' neurobiological processes. The findings could help to explain the evolution of social behavior in the animal kingdom, and shed light on the biochemistry of certain hormone systems that have developed similarly in both ants and humans.

from Top Health News -- ScienceDaily https://ift.tt/KehE5uU

Researchers have shown that within immune structures called the germinal centre, the mislocation of Tfh cells causes reduced capacity to respond well to vaccination with age. The research also identified that Tfh cells have a previously unappreciated role in supporting stromal cell responses to vaccines. The research demonstrates that age-dependent defects in the germinal centre response are reversible. These findings add to our understanding of the mechanisms behind a reduced immune response with age, allowing strategies to be developed to overcome or correct these to ensure the generation of robust immunological memory after vaccination.

from Top Health News -- ScienceDaily https://ift.tt/5PUOysN

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