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02/06/20

Researchers found that the neurons, or memory cells, involved in Pavlovian learning shift their behavior during the learning process and become more synchronized when a memory is formed -- a finding that helps better understand memory mechanisms and provides clues for the development of future therapies for memory-related diseases like dementia, autism and post-traumatic stress disorder (PTSD).

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A new study shows classrooms remain overlooked when it comes to the health risks of sitting still for too long. Researchers found most students don't realize the health risks can't be counteracted by later exercise, and perhaps unsurprisingly, students feel it is socially unacceptable to take a walk while the professor is still leading class. The researchers have solutions like building open classrooms and offering instructor-led stretch breaks.

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A growing body of research shows that the behavior of peers can significantly influence an individual's energy-related decisions, but why that occurs is less clear. A new article provides insights into the factors that underpin the effectiveness of peer influence - and how it might be used to promote more sustainable energy choices.

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Researchers have discovered that the genetic variant APOE4 -- long linked to dementia -- spurs the spread of harmful clumps of Parkinson's proteins through the brain. The findings suggest that therapies that target APOE might reduce the risk of dementia for people with Parkinson's disease.

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Steroids should be avoided in the treatment of the current novel coronavirus, experts have advised. A commentary article published in The Lancet concludes that, based on evidence from previous outbreaks of similar types of infection such as SARS, steroids provide little benefit to patients and could do more harm than good. They say that clinicians should still administer the treatment for conditions such as asthma and other inflammatory diseases.

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About 80 percent of Americans will experience low back pain at some point. Patients are often advised to manage their back pain with exercise and mind-body interventions. But, do they really help? Researchers compared and contrasted yoga, tai chi and qigong, and found them to be effective for treatment of low back pain, reporting positive outcomes such as reduction in pain or psychological distress such as depression and anxiety, reduction in pain-related disability, and improved functional ability.

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Eosinophilic chronic rhinosinusitis (ECRS) is a type of airway disease that involves nasal inflammation. Here, semaphorin protein was found to contribute to allergic reactions and development of nasal polyps in patients with ECRS. A research team found that an anti-semaphorin antibody could reduce nasal inflammation in a mouse model of ECRS and that semaphorin protein could be a new biomarker for ECRS in patients with nasal inflammation.

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The recognition of bacterial infections or foreign substances is mediated and controlled by the human immune system. This innate and adaptive immune system comprises the most important metabolic and cellular processes to fight against infections and other diseases. The immune system is also involved in the development of systemic diseases and cancer -- it is of utmost importance to further understand fundamental biochemical processes involved in the cellular reactions which can lead directly to novel therapies.

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Brain scientists have identified a causal mechanism of how novel stimuli promote learning. Novelty directly activates the dopamine system, which is responsible for associative learning. The findings have implications for improving learning strategies and for the design of machine learning algorithms.

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Recently there has been much discussion and many questions about vegan diets. Are vegan diets — which exclude meat, poultry, seafood, eggs, and dairy — healthful? Do they provide complete nutrition? Should I try one? Will it help me lose weight?

Many people around the world eat plant-based diets for a variety of reasons, some because meat is not readily available or affordable, others because of religious convictions or concerns about animal welfare. Health has become another reason people are moving to plant-based diets. And research supports the idea that plant-based diets, including vegan diets, provide health benefits.

What does the science say?

A recent meta-analysis, published in JAMA Internal Medicine, looked at nine observational studies totaling over 300,000 participants to see how plant-based diets (both vegan and vegetarian) relate to type 2 diabetes risk. The study found that those most closely following plant-based diets (emphasizing foods like whole grains, legumes, nuts, vegetables, and fruits, while de-emphasizing or eliminating animal foods such as meat, dairy, and eggs) had a 23% lower risk of developing type 2 diabetes.

In a 2016 study published in the American Journal of Clinical Nutrition, researchers analyzed the diets of over 26,000 men for nearly eight years. They found that vegan diets were linked with a 35% lower risk of prostate cancer compared to non-vegetarian diets.

And an extensive review of the literature published in The Lancet in February 2019 showed that a mostly plant-based diet could prevent approximately 11 million deaths per year globally, and could sustainably produce enough food for the planet’s growing population without further damage to the environment.

Finally, a position paper from the Academy of Nutrition and Dietetics noted that appropriately planned vegetarian (including vegan) diets are healthful, nutritionally adequate, and may provide health benefits for the prevention and treatment of certain diseases. It went on to say that these diets are appropriate for all life stages including pregnancy, lactation, infancy, childhood, adolescence, and older adulthood.

Careful planning is important for a vegan diet

While vegan diets can be healthy, you may have to do a little planning to balance a vegan plate and ensure you get enough protein, calcium, iron, and vitamin B12. Here are some foods and nutrients to pay special attention to.

Protein. A variety of vegan foods are rich in protein. They include soybean products (tofu, edamame, tempeh), seitan, lentils, beans or peas, nutritional yeast, spirulina, soy milk, cashew milk, nuts and seeds, nut and seed butters, veggie burgers, and meat alternatives.

Healthy fats. Healthy, vegan sources of fats include various oils (olive, canola, sunflower, safflower, soybean, and corn), nuts and seeds, avocado, flaxseeds, and chia seeds. It is important for vegans to eat foods containing alpha-linolenic acid, a type of fat that can be converted into essential omega-3 fats (DHA and EPA) in your body. The richest sources of alpha-linolenic acid are flaxseeds and flax oil, chia seeds, hempseed oil, walnuts or walnut oil, canola oil, and soybean oil. If you do not consume these items daily, consider consuming a flaxseed oil supplement.

Calcium. Without dairy, an unbalanced vegan diet can lack calcium. Aim for one to two cups per day of well-absorbed sources of calcium such as tofu, calcium-enriched fruit juice, cooked Chinese cabbage, turnip greens, mustard greens, collard greens, or fortified plant milks (soy, almond, cashew). If you fall short of the daily goal, you may need a calcium supplement.

Vitamin B12: There are only two reliable sources of vitamin B12 for vegans; fortified foods and supplements. Examples of B12-fortified foods include: fortified plant milks (soy, almond, cashew), meat alternatives, fortified cereals, and nutritional yeast. If you are not consuming about six micrograms per day, talk to your doctor about taking a vitamin B12 supplement.

Iodine. Vegans who do not consume key vegan sources of iodine, such as iodized salt or sea vegetables, may be at risk for iodine deficiency. Sea salt, kosher salt, and salty seasoning such as tamari are generally not iodized.

Round out your meals with a variety of vegetables, fruits, and whole grains.

Ideas for balanced vegan meals

Breakfast:

  • Quinoa porridge made with almond milk, almonds, and blueberries
  • Veggie “omelet” made with shredded tofu, soy cheese, chopped vegetables; 1 slice of whole grain toast
  • Refried pinto beans in a small whole-grain tortilla with tomatoes, onions, and fresh salsa

Lunch:

  • Vegan pizza made with whole-wheat crust, tomato slices, soy cheese, mushrooms, broccoli, peppers, and onions
  • Mediterranean barley salad: cooked barley with celery, red onion, red and orange bell pepper, cannellini beans, with olive oil and vinegar dressing on a bed of fresh baby spinach
  • Lentil stew

Dinner:

  • Vegetarian chili made with red, black, and kidney beans, canned tomatoes, celery, onions, carrots, and spices
  • Stir-fried tofu with broccoli, cauliflower, asparagus, and yellow peppers topped with peanuts over brown rice
  • Whole-wheat pasta with garbanzo beans and peas topped with a pesto sauce; kale salad with artichoke hearts, asparagus, and balsamic vinaigrette

Snacks:

  • Nuts, hummus and carrots, bean dip with whole-grain chips, apple with peanut butter, sunflower or pumpkin seeds, baba ghanoush with whole wheat pita bread

The post With a little planning, vegan diets can be a healthful choice appeared first on Harvard Health Blog.



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Is free will just an illusion? For decades, a signal from the brain called the 'readiness potential' has been interpreted to mean that free will may be an illusion. Backed by signals from the brain and lungs, scientists have discovered that the readiness potential is in fact coupled to breathing and that acts of free will happen as you exhale -- providing an unexpected perspective on free will.

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