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06/02/21

Researchers have developed a new process using machine learning algorithms to match the signals of a microbe's metabolites with its genomic signals and identify which likely correspond to a natural product. Knowing that, researchers are better equipped to isolate the natural product to begin developing it for a possible drug and possibly reinvigorate the search for natural product drugs.

from Top Health News -- ScienceDaily https://ift.tt/3fKjffd

The mystery of why salamanders can regenerate a lost limb, but adult mammals cannot has fascinated observers for thousands of years. Now, a team of scientists has come a step closer to unraveling that mystery with the discovery of differences in molecular signaling that promote regeneration in the axolotl, a highly regenerative salamander, while blocking it in the adult mouse.

from Top Health News -- ScienceDaily https://ift.tt/3i9bssV

The organization of the human genome relies on physics of different states of matter - such as liquid and solid. The findings reveal how the physical nature of the genome changes as cells transform to serve specific functions and point to new ways to potentially better understand disease and to create improved therapies for cancer and genetic disorders.

from Top Health News -- ScienceDaily https://ift.tt/3cbfvks

Nerve cells of the vagus nerve fulfill opposing tasks. The gut and the brain communicate with each other in order to adapt satiety and blood sugar levels during food consumption. The vagus nerve is an important communicator between these two organs. Researchers now took a closer look at the functions of the different nerve cells in the control center of the vagus nerve, and discovered something very surprising: although the nerve cells are located in the same control center, they innervate different regions of the gut and also differentially control satiety and blood sugar levels. This discovery could play an important role in the development of future therapeutic strategies against obesity and diabetes.

from Top Health News -- ScienceDaily https://ift.tt/3yYHYnl

Humans can observe what and where something happens around them with their hearing, as long as sound frequencies lie between 20 Hz and 20 000 Hz. Researchers have now developed a new audio technique that enables people to also hear ultrasonic sources that generate sound at frequencies above 20,000 Hz with simultaneous perception of their direction.

from Top Health News -- ScienceDaily https://ift.tt/3pe6VH2

A new study has identified a protein that could be the key to improving treatment outcomes after a heart attack. It suggests that protein kinase A (PKA) plays a role in heart muscle cell necrosis, a major type of cell death that commonly occurs after reperfusion therapy, the treatment used to unblock arteries and restore blood flow after a heart attack.

from Top Health News -- ScienceDaily https://ift.tt/34Hko0A

A healthy diet around the time of conception through the second trimester may reduce the risk of several common pregnancy complications, suggests a new study. Expectant women in the study who scored high on any of three measures of healthy eating had lower risks for gestational diabetes, pregnancy-related blood pressure disorders and preterm birth.

from Top Health News -- ScienceDaily https://ift.tt/34DxGLA

Physical activity is the optimal first treatment choice for adults with mild to moderately elevated blood pressure and blood cholesterol who otherwise have low heart disease risk. About 21% of adults in the US with mild to moderately raised blood pressure and 28-37% of those with mild to moderate elevated cholesterol levels may be best served by a prescription for lifestyle-only treatment, which includes increasing physical activity.

from Top Health News -- ScienceDaily https://ift.tt/3uKz3D1

Genetically Modified CropsA new study is causing fresh doubts about the safety of genetically modified crops. The research found Bt toxin, which is present in many GM crops, in human blood.

Bt toxin makes crops toxic to pests, but it has been claimed that the toxin poses no danger to the environment and human health; the argument was that the protein breaks down in the human gut. But the presence of the toxin in human blood shows that this does not happen.

India Today reports:

“Scientists ... have detected the insecticidal protein ...  circulating in the blood of pregnant as well as non-pregnant women. They have also detected the toxin in fetal blood, implying it could pass on to the next generation.”



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