Health & Fitness

Blocking a receptor called P2X7 significantly reduced inflammation in human brain tissue, revealing a potential new treatment strategy for neurological and psychiatric disorders. The discovery could help researchers repurpose existing drugs for conditions including traumatic brain injury, Alzheimer’s, Parkinson’s, depression, and schizophrenia.

from Top Health News -- ScienceDaily https://ift.tt/i0w6mRh

Cannabinoids may intensify anxiety by removing a natural brake on specific neurons in the brain’s fear center, particularly during stressful situations. In mice, shutting down those neurons sharply reduced cannabinoid-related anxious behavior.

from Top Health News -- ScienceDaily https://ift.tt/0w34GBT

In a small study, sleeping near the scent of Hinoki root essential oil was linked to fewer nighttime awakenings, better morning alertness, and brain-wave changes associated with smoother sleep onset. The findings suggest an overlooked forestry byproduct could someday become a natural ingredient in sleep and relaxation products.

from Top Health News -- ScienceDaily https://ift.tt/xLp6k5E

Cancer immunotherapy can lose its punch when tumor-fighting T cells become exhausted, but researchers may have found a way to keep them going longer. Scientists at Memorial Sloan Kettering Cancer Center identified a signaling molecule called MEK that can push T cells to burn through their energy while producing cancer-killing proteins. In animal and laboratory studies, blocking MEK helped the cells conserve energy, survive longer, and remain active even in the harsh environment around tumors.

from Top Health News -- ScienceDaily https://ift.tt/Z9vlUSu

Scientists have discovered that E-cadherin, a protein best known as the “glue” holding cells and tissues together, has a surprising second job: helping epithelial cells swallow nearby dead cells. Using live zebrafish and mouse embryos, researchers found that cells can dramatically reshape their lower surfaces to engulf cellular debris while keeping their upper surfaces stable, allowing protective barriers to remain sealed.

from Top Health News -- ScienceDaily https://ift.tt/yeVxUzH

Researchers found that just 20 minutes of comfortable walking can rapidly stimulate the gut. Within one to two minutes after exercise, bowel sounds became stronger, more frequent, and lasted longer, suggesting increased intestinal movement. The boost was brief, fading within a few minutes, but it may help explain why walking can provide relief from constipation.

from Top Health News -- ScienceDaily https://ift.tt/lYo1vOR

A vitamin D analog may help break down pancreatic cancer’s protective defenses, potentially making tumors more vulnerable to chemotherapy and immune attack. A small clinical trial found encouraging responses, especially in patients whose tumors had high levels of the vitamin D receptor.

from Top Health News -- ScienceDaily https://ift.tt/IKfWxYX