Health & Fitness

Researchers have identified two brain receptors that help the brain clear away amyloid beta, a hallmark of Alzheimer’s disease. By stimulating these receptors in mice, scientists increased levels of a natural amyloid-breaking enzyme, reduced buildup in the brain, and improved memory-related behavior. Because these receptors are common drug targets, the findings could open the door to affordable pill-based treatments with fewer side effects.

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As cash transfer programs expand across the United States, critics often warn that giving people money could spark reckless behavior, leading to injuries or even deaths. But a sweeping 11-year analysis of Alaska’s long-running Permanent Fund Dividend program tells a different story. Researchers examined statewide hospital records and death data and found no increase in traumatic injuries or unnatural deaths after annual payments were distributed.

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A parasite that may already be hiding in your brain has a shocking survival trick: it can infect the very immune cells sent to destroy it. Yet most people never get sick, and new research from UVA Health reveals why. Scientists discovered that when Toxoplasma gondii invades CD8+ T cells — key defenders of the immune system — those cells can trigger a self-destruct mechanism powered by an enzyme called caspase-8. By sacrificing themselves, the infected cells also wipe out the parasite inside them.

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A sweeping review of global research suggests that exercise—especially aerobic activities like running, swimming, and dancing—can be one of the most powerful ways to ease depression and anxiety. Across tens of thousands of people aged 10 to 90, exercise consistently reduced symptoms, often matching or even outperforming medication and talk therapy.

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Researchers have uncovered the enzyme behind chromothripsis, a chaotic chromosome-shattering event seen in about one in four cancers. The enzyme, N4BP2, breaks apart DNA trapped in tiny cellular structures, unleashing a burst of genetic changes that can help tumors rapidly adapt and resist therapy. Blocking the enzyme dramatically reduced this genomic destruction in cancer cells.

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Scientists have uncovered a hidden partnership between pancreatic cancer and the nervous system. Support cells in the pancreas lure nerve fibers, which then release signals that accelerate early cancer growth. This creates a self-sustaining loop that helps tumors take hold. Blocking the nerve activity significantly reduced tumor growth in experiments, suggesting a new treatment strategy.

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Psychedelics can quiet the brain’s visual input system, pushing it to replace missing details with vivid fragments from memory. Scientists found that slow, rhythmic brain waves help shift perception away from the outside world and toward internal recall — almost like dreaming while awake. By imaging glowing brain cells in mice, researchers watched this process unfold in real time.

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