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UC Davis researchers created brand-new psychedelic-like compounds by shining UV light on amino acid-based molecules. These compounds activated key serotonin receptors tied to brain plasticity and mental health benefits, but surprisingly did not cause hallucination-like behavior in animal tests. Scientists say the discovery could lead to future treatments for depression, PTSD, and addiction without the intense psychedelic experience.

from Top Health News -- ScienceDaily https://ift.tt/WtB7HF8

Researchers found a new way to kill harmful “zombie” cells that linger after chemotherapy and help cancers become more aggressive. These senescent cells survive by relying on a protective protein called GPX4, even while sitting on the edge of a deadly iron-triggered collapse. New drugs remove that protection, causing the cells to self-destruct. In mice, the approach reduced tumor size and boosted survival, hinting at a promising new cancer therapy.

from Top Health News -- ScienceDaily https://ift.tt/rVUXi4x

Scientists at McGill University have uncovered a hidden molecular “switch” that turns on a powerful calorie-burning system in brown fat — the body’s heat-generating fat linked to metabolism and weight control. The breakthrough centers on glycerol, a molecule released when fat is broken down in the cold, which activates an enzyme called TNAP and triggers an alternative heat-producing pathway that scientists had struggled to explain for years.

from Top Health News -- ScienceDaily https://ift.tt/nSfG3LO

Staying strong may be one of the biggest secrets to living longer — especially for older women. A major study of more than 5,000 women found that simple signs of muscle strength, like a firm hand grip or the ability to quickly stand up from a chair, were strongly linked to lower risk of death over the next eight years.

from Top Health News -- ScienceDaily https://ift.tt/Ed5WzoS

Ultra-processed foods may be doing far more damage than many people realize. A major new European cardiology report warns that people who eat the most ultra-processed foods face significantly higher risks of heart disease, irregular heart rhythms, obesity, diabetes, high blood pressure, and even cardiovascular death. Researchers say these industrially manufactured foods — often packed with sugar, salt, unhealthy fats, and additives — can disrupt metabolism, trigger inflammation, and promote overeating, even when marketed as “healthy.”

from Top Health News -- ScienceDaily https://ift.tt/yfqJPED

Scientists have uncovered a striking brain difference linked to psychopathy: people with psychopathic traits were found to have a striatum — a brain region tied to reward, motivation, and decision-making — that was about 10% larger on average than those without such traits. Using MRI scans and psychological assessments on 120 participants, researchers connected this enlarged brain region to thrill-seeking, impulsive behavior, and a stronger drive for stimulation.

from Top Health News -- ScienceDaily https://ift.tt/mRHX2qp

Scientists have uncovered a hidden “stop-scratching” signal in the nervous system that tells your brain when enough scratching is enough. The discovery centers on a molecule called TRPV4, which acts like part of an internal braking system for itch relief. In experiments involving chronic itch similar to eczema, mice missing this signal scratched less often—but when they did scratch, they couldn’t stop.

from Top Health News -- ScienceDaily https://ift.tt/9eGJgfs

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