Health & Fitness

Johns Hopkins scientists uncovered microscopic “nanotube” channels that neurons use to transfer toxic molecules. While this process clears waste, it can also spread harmful proteins like amyloid-beta. Alzheimer’s-model mice showed more nanotubes early on, hinting at a link to disease development. Researchers hope to one day control nanotube formation as a potential therapy.

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A new human liver organoid microarray developed by Cincinnati Children’s and Roche recreates immune-driven liver injury in the lab. Built from patient-derived stem cells and immune cells, it accurately models how genetics influence drug reactions. The system replicated flucloxacillin-related toxicity seen only in people with a specific genetic variant, marking a major step toward predictive, patient-tailored drug safety testing.

from Top Health News -- ScienceDaily https://ift.tt/lYErL2V

Endurance exercise may train the immune system as much as the muscles. Older adults with decades of running or cycling had immune cells that functioned better and aged more slowly. Their inflammation levels were lower and their cells resisted fatigue even under stress. The findings point to a direct link between lifelong fitness and healthier immune regulation.

from Top Health News -- ScienceDaily https://ift.tt/YRonqJs