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08/03/21

fibromyalgiaResearchers have detected abnormalities in the brains of people with fibromyalgia, a chronic condition whose symptoms include muscle pain and fatigue.

Some researchers have suggested that the pain of fibromyalgia is the result of depression, but the new study suggests otherwise. The abnormalities were independent of anxiety and depression levels.

Researchers evaluated 20 women diagnosed with fibromyalgia and 10 healthy women without the condition who served as a control group. The researchers performed brain imaging called single photon emission computed tomography, or SPECT.

The imaging showed that women with the syndrome had "brain perfusion" -- blood flow abnormalities in their brains. The abnormalities were directly correlated with the severity of disease symptoms.

An increase in blood flow was found in the brain region known to discriminate pain intensity.

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cell phone dangers, wifi, wireless, internet, allergies, Electromagnetic Hypersensitivity Syndrome, EHS, multiple chemical sensitivity, MCSElectromagnetic Hypersensitivity Syndrome (EHS) is a condition in which people are highly sensitive to electromagnetic fields. In an area such as a wireless hotspot, they experience pain or other symptoms.

People with EHS experience a variety of symptoms including headache, fatigue, nausea, burning and itchy skin, and muscle aches. These symptoms are subjective and vary between individuals, which makes the condition difficult to study, and has left experts divided about the validity of such claims.

More than 30 studies have been conducted to determine what link the condition has to exposure to electromagnetic fields from sources such as radar dishes, mobile phone signals and, Wi-Fi hotspots.



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The average American eats roughly 22 teaspoons of added sugar a day -- more than three times the recommended amount for women and more than double the recommended amount for men. Although this overconsumption is known to contribute to diabetes and other disorders, the exact ways in which eating too much sugar sets the stage for metabolic diseases on a cellular level has been less clear. Now, a team has found that surplus sugar may cause our cellular powerplants -- called mitochondria -- to become less efficient, reducing their energy output.

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Researchers report that infantile spasms, a rare but serious seizure disorder in babies, appear to be the result of a molecular pathway gone awry. In their study of a mouse model of the disorder, the researchers discovered that genetic mutations associated with the disease impair a pathway that is involved in building new synapses in the hippocampus, a brain region essential to learning and memory.

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Bioengineers have developed a technology capable of revealing the protein-protein interactions (PPI) among thousands of proteins in a cell, in a single experiment. The tool, called PROPER-seq (protein-protein interaction sequencing), allows researchers to map the PPI network from their cells of interest within several weeks, without any specialized resources such as antibodies or pre-made gene libraries.

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A key element to slowing metastasis in ovarian cancer is understanding the mechanisms of how tumor cells invade tissues. Biophysics researchers explain how microscopic defects in how healthy cells line up can alter how easily ovarian cancer cells invade tissue. Using an experimental model, the group found that disruptions in the normal cellular layout, called topological defects, affect the rate of tumor cell invasion.

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Imagining a song triggers similar brain activity as moments of silence in music, according to new research. The results reveal how the brain continues responding to music, even when none is playing, and provide new insights into how human sensory predictions work.

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When we speak, we use our auditory and somatosensory systems to monitor the results of the movements of our tongue or lips. Since we cannot typically see our own faces and tongues while we speak, however, the potential role of visual feedback has remained less clear. Researchers explore how readily speakers will integrate visual information about their tongue movements during a speech motor learning task.

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Scientists have extensively studied how gastric juices in the stomach break down ingested food and other substances. However, less is known about how complex flow patterns and mechanical stresses in the stomach contribute to digestion. Researchers built a prototype of an artificial antrum to present a deeper understanding of how physical forces influence food digestion based on fluid dynamics. They reveal a classifying effect based on the breakup of liquid drops combined with transport phenomena.

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Researchers identified an inhibitor that showed promise against metastatic castration-resistant prostate cancer cells. From there, they continued to untangle the web to discover multiple levels of cellular processes that were preventing the immune system from mounting a response. Break past them with this inhibitor and suddenly what's considered an immune cold tumor turns red hot.

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A new study details the structure of a critical enzyme present in SARS-CoV-2, the coronavirus that causes COVID-19. This enzyme removes nucleoside antiviral medications from the virus's RNA, rendering many treatments ineffective. Scientists could use data uncovered in the new study to find ways to inhibit the enzyme, possibly leading to more effective treatments.

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A new study found a significant association between cholesterol-lowering drugs commonly known as statins and survival rates of triple-negative breast cancer patients. Since statins are low in cost, easy to access and produce minimal side effects, this could have an important impact on outcomes for this aggressive disease.

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Researchers have discovered that a cellular phenomenon called cryptic transcription, which had been previously described and linked to aging in yeasts and worms, is also involved in mammalian aging. They also discovered a mechanism that triggers the phenomenon in mammals.

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Clinicians frequently order preoperative urinalyses for patients scheduled to undergo many common procedures. A new study finds that nearly nine out of 10 of preoperative urinalyses are unnecessary. Overuse of low-value screening test wastes money, can harm patients and may contribute to the growing problem of antibiotic resistance.

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Six weeks of physical exercise led to changes in the epigenetic information of skeletal muscle cells in young men. These changes took place in areas of the genome that have been linked to disease. Scientists say their research shows how exercise remodels DNA in skeletal muscle, so that new signals are established to keep the body healthy.

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