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05/03/23

Gene-editing therapy aimed at two targets -- HIV-1, the virus that causes AIDS, and CCR5, the co-receptor that helps the virus get into cells -- can effectively eliminate HIV infection, new research shows. The study combines a dual gene-editing strategy with antiretroviral drugs to cure animals of HIV-1.

from Top Health News -- ScienceDaily https://ift.tt/EvRKo7h

Immunotherapy has redefined cancer treatment, but not all patients experience the same benefit when treated. New research in mice identifies how gut bacteria alter the body's response to a common form of cancer immunotherapy. The animals' gut microbiota lowered the expression of two immune molecules, one previously unknown to play a role in cancer. • Using antibodies to block the activity of either molecule, or the interplay between them, enhanced response to cancer immunotherapy. • The findings can inform the design of treatments that boost the efficacy of cancer immunotherapy among patients with suboptimal response.

from Top Health News -- ScienceDaily https://ift.tt/c5wv4aN

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