Health & Fitness

Previous and similar research has focused on Western countries and diets that combined harmful, ultra-processed foods with nutrient-dense foods. This research was global in scope and focused on foods commonly considered to be healthy. Researchers derived a diet score from PHRI's ongoing, large-scale global Prospective Urban and Rural Epidemiological (PURE) study, then replicated that in five independent studies to measure health outcomes in different world regions and in people with and without prior CVD.

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Human cells evolving in the laboratory undergo a series of predictable, sequential genetic changes that lead to pre-cancer. Blocking these changes may allow intervention before cancer occurs.

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A novel molecular pathway to explain how a mutation in the gene ACTA2 can cause individuals in their 30s -- with normal cholesterol levels and no other risk factors -- to develop coronary artery disease has now been identified,.

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The prevalence of moderate or severe joint pain due to arthritis varies strikingly across American states, ranging from 6.9% of the population in Minnesota to 23.1% in West Virginia, according to a new study.

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As a psychiatric disorder with onset in adulthood, schizophrenia is thought to be triggered by some combination of environmental factors and genetics, although the exact cause is still not fully understood. Researchers have now found a correlation between schizophrenia and somatic copy-number variants, a type of mutation that occurs early in development but after genetic material is inherited. This study is one of the first to rigorously describe the relationship between somatic -- not inherited -- genetic mutations and schizophrenia risk.

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Global efforts to reduce infectious disease rates must have a greater focus on older children and adolescents after a shift in disease burden onto this demographic, according to a new study.

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Osteoarthritis is the most common degenerative joint disease, affecting 22% of adults over 40 globally. Although the condition has been extensively studied through a medical perspective, the molecular changes associated with osteoarthritis remain unclear. In a new study, researchers have used a combination of techniques to track the progression of the disease and the changes associated with it.

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