Health & Fitness

Preschoolers with ADHD are often given medication right after diagnosis, against medical guidelines that recommend starting with behavioral therapy. Limited access to therapy and physician pressures drive early prescribing, despite risks and reduced effectiveness in young children.

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Scientists at UC San Diego have identified a new drug, ION224, that could transform the treatment of MASH, a dangerous form of fatty liver disease tied to obesity and diabetes. By blocking a key liver enzyme, the drug reduces fat and inflammation, halting the root causes of liver damage. In a year-long clinical trial, patients showed major improvements without serious side effects, offering hope to millions affected worldwide.

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Researchers from the University of Waterloo discovered that measuring long-term stress through children’s hair samples can reveal early signs of mental health risks in those living with chronic physical illnesses. Children with persistently high cortisol were more likely to struggle with anxiety, depression, and behavioral challenges, while those whose stress markers declined showed fewer problems.

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Dry eyes are far more common than previously believed, with over half of adults in the US and Europe experiencing symptoms, yet most remain undiagnosed for years. The large-scale NESTS study reveals that sufferers often endure daily discomfort that disrupts work, driving, and even surgery outcomes. Many accept the condition as part of aging, unaware that simple treatments could provide relief.

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A massive study of over 4 million adults has revealed that cannabis use may nearly quadruple the risk of developing diabetes. Despite some earlier suggestions that cannabis might have metabolic benefits, this large analysis found significantly higher diabetes rates among users, even after adjusting for other health factors.

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New research from Denmark challenges long-held assumptions about body weight and health, revealing that being overweight—or even moderately obese—does not necessarily increase the risk of death compared to those at the upper end of the "normal" BMI range. In fact, those who are underweight or at the lower end of the so-called healthy spectrum faced higher risks.

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Scientists in Tokyo have uncovered “Inocles,” massive strands of extrachromosomal DNA hidden inside bacteria in human mouths. These giants, overlooked by traditional sequencing, could explain how oral microbes adapt, survive, and impact health. Found in nearly three-quarters of people, Inocles carry genes for stress resistance and may even hint at links to diseases like cancer, opening a whole new frontier in microbiome research.

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