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Researchers report that they found high levels of the protein Fli-1 in the brains of deceased Alzheimer's patients. Blocking Fli-1's action in a mouse model of Alzheimer's disease reversed mental loss and reduced the brain inflammation and amyloid-beta clumping that are hallmarks of Alzheimer's disease. Although clinical translation of this finding is likely years off, the study suggests Fli-1 is a promising therapeutic target for Alzheimer's disease.

from Top Health News -- ScienceDaily https://ift.tt/C7kVGj1

Tuberculosis (TB) is the second most common cause of death worldwide by an infectious pathogen (after Covid-19), but many aspects of its long history with humans remain controversial. Researchers found that ancient TB discovered in archaeological human remains from South America is most closely related to a variant of TB associated today with seals, but surprisingly these cases were found in people who lived nowhere near the coast. This implies that these cases were not the result of direct transmission from seals, and instead one, or more, spillover events were likely to be the primary drivers of human infection.

from Top Health News -- ScienceDaily https://ift.tt/mDGNXxk

Women with overactive bladder are frequently frustrated with treatment, which leads to discontinuation of therapy. Asynchronous telehealth visits keep women engaged in follow-up care, accelerates trials of different medications and reinforces behavioral changes. The women in this pilot study reported improvement in symptoms and high satisfaction with asynchronous visits.

from Top Health News -- ScienceDaily https://ift.tt/1oiTgxv

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