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In many neurodegenerative diseases, proteins clump in the brain, forming so-called amyloid fibrils. Yet there exists a cellular defence mechanism that counteracts this process and even dissolves fibrils already formed. The mechanism is based on the activity of molecular helpers, so-called chaperones of the heat shock protein 70 family.

from Top Health News -- ScienceDaily https://ift.tt/32As8ke

Even though repeated hits to the head are common in professional sports, the long-term effects of concussions are still poorly understood. While many believe that professional athletes who experience multiple concussions will end up with severe cognitive impairment later in life, a new study suggests that may not necessarily be the case.

from Top Health News -- ScienceDaily https://ift.tt/3eOqyAe

Researchers showed that na enzyme functions in genome maintenance by preventing double-stranded breaks in DNA during brain development in mice. In mice lacking this enzyme, these breaks occurred during epigenetic regulation of gene expression in the developing hippocampus, peaking two weeks after birth. The increased breaks were associated with abnormal neuronal dendrites and poor memory ability.

from Top Health News -- ScienceDaily https://ift.tt/3njZT19

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