Changes in how cholesterol breaks down in the body may accelerate progression of dementia

The blood-brain barrier is impermeable to cholesterol, yet high blood cholesterol is associated with increased risk of Alzheimer's disease and vascular dementia. However, the underlying mechanisms mediating this relationship are poorly understood. A new study suggests that disturbances in the conversion of cholesterol to bile acids may play a role in the development of dementia.

from Top Health News -- ScienceDaily https://ift.tt/3yK0JuR