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A promising path to fighting COVID and other coronaviruses may have been based on a serious mistake. Scientists had zeroed in on a part of the virus called the NiRAN domain, believed to be a powerful target for new antiviral drugs. But when a Rockefeller team revisited a highly cited 2022 study, they found the evidence didn’t hold up. Key molecules shown in the original virus model were actually missing. Their discovery could help prevent wasted time and resources in the race to develop better treatments—and highlights how even one bad blueprint can throw off years of research.

from Top Health News -- ScienceDaily https://ift.tt/W67Iw9x

Scientists have discovered that the bacteria behind Lyme disease and anaplasmosis have a sneaky way of surviving inside ticks—they hijack the tick’s own cell functions to steal cholesterol they need to grow. By tapping into a built-in protein pathway, the bacteria keep themselves alive until they can infect a new host. The research opens the door to new methods of stopping these diseases before ticks ever get the chance to bite. A new web tool also reveals that this trick might be used by other blood-feeding bugs too.

from Top Health News -- ScienceDaily https://ift.tt/qCHpieG

Stanford researchers discovered that dialing down an overactive enzyme, LRRK2, can regrow lost cellular “antennae” in key brain cells, restoring vital dopamine communication and neuroprotective signals in a mouse model of genetic Parkinson’s. After three months on the LRRK2-blocking drug MLi-2, damaged circuits revived and early signs of neuronal recovery emerged, hinting that timely treatment could not only halt but reverse disease progression—and perhaps benefit other Parkinson’s forms.

from Top Health News -- ScienceDaily https://ift.tt/nkXBG0o

In a leap toward sustainable desalination, researchers have created a solar-powered sponge-like aerogel that turns seawater into drinkable water using just sunlight and a plastic cover. Unlike previous materials, this new 3D-printed aerogel maintains its efficiency at larger sizes, solving a key scalability issue. In outdoor tests, it produced clean water directly from the ocean without any electricity, pointing to a future of low-cost, energy-free freshwater production.

from Top Health News -- ScienceDaily https://ift.tt/DTx7pqc

Scientists at UC Davis discovered a small genetic difference that could explain why humans are more prone to certain cancers than our primate cousins. The change affects a protein used by immune cells to kill tumors—except in humans, it’s vulnerable to being shut down by an enzyme that tumors release. This flaw may be one reason treatments like CAR-T don’t work as well on solid tumors. The surprising twist? That mutation might have helped our brains grow larger over time. Now, researchers are exploring ways to block the enzyme and give our immune system its power back.

from Top Health News -- ScienceDaily https://ift.tt/9DcmAQb

A sweeping review of more than a century’s research upends the popular notion that left-handers are naturally more creative. Cornell psychologist Daniel Casasanto’s team sifted nearly a thousand studies, ultimately finding no consistent advantage for lefties on standard divergent-thinking tests—and even a slight edge for right-handers in some. The myth appears to thrive on coincidence: left-handedness is rare and so is creative genius, plus lefties’ overrepresentation in art and music gets cherry-picked while other professions are ignored.

from Top Health News -- ScienceDaily https://ift.tt/MDzFwSg

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