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Stanford researchers discovered that dialing down an overactive enzyme, LRRK2, can regrow lost cellular “antennae” in key brain cells, restoring vital dopamine communication and neuroprotective signals in a mouse model of genetic Parkinson’s. After three months on the LRRK2-blocking drug MLi-2, damaged circuits revived and early signs of neuronal recovery emerged, hinting that timely treatment could not only halt but reverse disease progression—and perhaps benefit other Parkinson’s forms.

from Top Health News -- ScienceDaily https://ift.tt/nkXBG0o

In a leap toward sustainable desalination, researchers have created a solar-powered sponge-like aerogel that turns seawater into drinkable water using just sunlight and a plastic cover. Unlike previous materials, this new 3D-printed aerogel maintains its efficiency at larger sizes, solving a key scalability issue. In outdoor tests, it produced clean water directly from the ocean without any electricity, pointing to a future of low-cost, energy-free freshwater production.

from Top Health News -- ScienceDaily https://ift.tt/DTx7pqc

Scientists at UC Davis discovered a small genetic difference that could explain why humans are more prone to certain cancers than our primate cousins. The change affects a protein used by immune cells to kill tumors—except in humans, it’s vulnerable to being shut down by an enzyme that tumors release. This flaw may be one reason treatments like CAR-T don’t work as well on solid tumors. The surprising twist? That mutation might have helped our brains grow larger over time. Now, researchers are exploring ways to block the enzyme and give our immune system its power back.

from Top Health News -- ScienceDaily https://ift.tt/9DcmAQb

A sweeping review of more than a century’s research upends the popular notion that left-handers are naturally more creative. Cornell psychologist Daniel Casasanto’s team sifted nearly a thousand studies, ultimately finding no consistent advantage for lefties on standard divergent-thinking tests—and even a slight edge for right-handers in some. The myth appears to thrive on coincidence: left-handedness is rare and so is creative genius, plus lefties’ overrepresentation in art and music gets cherry-picked while other professions are ignored.

from Top Health News -- ScienceDaily https://ift.tt/MDzFwSg

Scientists have achieved an unprecedented look into how the human immune system attacks a transplanted pig kidney, using spatial molecular imaging to map immune activity down to the cellular level. They discovered early signs of rejection within 10 days and pinpointed key immune players—like macrophages—driving the response. Even more exciting: when targeted therapies were applied, the immune assault weakened. As U.S. clinical trials of pig kidney transplants begin, this breakthrough offers hope for overcoming the immune barrier that has long stood in the way of xenotransplantation.

from Top Health News -- ScienceDaily https://ift.tt/R9YHb6r

Scientists have discovered a stealthy mechanism that cytomegalovirus (CMV)—the leading infectious cause of birth defects in the U.S.—uses to infiltrate blood vessel cells while evading immune detection. The virus forms a hidden protein complex that acts like a molecular “backdoor,” allowing it to bypass the immune system’s defenses. This newly identified pathway may explain why vaccine efforts have failed for decades and opens the door to targeted therapies that could finally prevent CMV-linked birth defects in newborns and protect vulnerable patients.

from Top Health News -- ScienceDaily https://ift.tt/1dGbpyF

USC researchers have found a promising new brain scan marker that could better detect Alzheimer’s risk — but only for some. The tau-based benchmark works in Hispanic and White populations when paired with another Alzheimer’s protein, amyloid, but falls short for Black participants, revealing critical gaps in current diagnostics.

from Top Health News -- ScienceDaily https://ift.tt/OMPqDSB

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