Health & Fitness

FDA has cleared an investigational new drug (IND) application to study switchable chimeric antigen receptor T cell (sCAR-T) therapy (CLBR001 + SWI019) in patients with autoimmune conditions. Patient recruitment for the phase 1 trial will begin soon (NCT06913608). The phase 1 clinical trial will evaluate the safety and efficacy of CLBR001 + SWI019 in patients with myositis, systemic sclerosis, lupus and rheumatoid arthritis, with the potential to expand to other indications in the future.

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A study has shown that Europe has adapted better to low temperatures than to high temperatures over the last two decades. The relative risk of mortality at the coldest temperatures has decreased by 2% per year since 2003, while the risk from extreme heat has only fallen by 1% per year.

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A small protein involved in neurodegeneration leading to Parkinson's disease also drives a type of skin cancer known as melanoma, according to new research.

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Shifting cultural perceptions of beauty could drive 'lip dysmorphia', so psychologists tested the response of 32 people to altered images of lips to see how they responded. The results were surprising.

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A new, exploratory study has revealed statistical links between the performance of medical detection dogs and their scores on behavioral and affective tests, finding that more 'optimistic' dogs tended to perform better overall on detection tasks, but 'pessimistic' dogs had higher scent detection specificity.

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Numerous studies have shown that working the night shift is associated with serious health risks, including to the heart. However, a new study suggests that eating only during the daytime could help people avoid the health risks associated with shift work.

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A comprehensive study of the long-term health impacts of flooding -- via analysis of over 300 million hospitalizations records in eight countries prone to flooding events -- has found an increased risk of 26 per cent of all diseases serious enough to require hospitalization. This impact on the health of communities lasts up to seven months post event.

from Top Health News -- ScienceDaily https://ift.tt/KetcXiS