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This study builds on decades of work showing that the protein IL-24 attacks cancer broadly, and is the first to deliver the protein using T cells. This approach is in contrast to CAR-T cells, which are built to recognize proteins on the surface of cancer cells and haven't been successful against solid tumors. Mice with prostate cancer experienced shrinkage of the original tumor as well as distant metastases following treatment with IL-24 T cells.

from Top Health News -- ScienceDaily https://ift.tt/3aTWUsz

Researchers have created a new gene editing tool called Retron Library Recombineering (RLR) that can generate up to millions of mutations simultaneously, and 'barcodes' mutant bacterial cells so that the entire pool can be screened at once. It can be used in contexts where CRISPR is toxic or not feasible, and results in better editing rates.

from Top Health News -- ScienceDaily https://ift.tt/3e4pwl1

'Feel-good films' are usually dismissed by film critics as being sentimental and without intellectual merit. But their popularity with audiences, who seek them out precisely because of their 'feel-good' qualities, tells a more favorable story. Now, for the first time, this popular movie genre has been examined scientifically.

from Top Health News -- ScienceDaily https://ift.tt/3xzo5Tk

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