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Researchers have discovered a new metabolic vulnerability in a highly aggressive form of non-small cell lung cancer (NSCLC). These findings could pave the way for new treatments for patients with mutations in two key genes - KRAS and LKB1. Patients whose tumors contain both of these mutations, known as KL tumors, have poor outcomes and usually do not respond to immunotherapy.

from Top Health News -- ScienceDaily https://ift.tt/2MtMp5U

Lithium is considered the gold standard for treating bipolar disorder (BD), but nearly 70 percent of people with BD don't respond to it. This leaves them at risk for debilitating, potentially life-threatening mood swings. Researchers have found that the culprit may lie in gene activity -- or lack of it.

from Top Health News -- ScienceDaily https://ift.tt/2MBZESi

A new study following young adult drinkers for 10 years has found that individuals who reported the highest sensitivity to alcohol's pleasurable and rewarding effects at the start of the trial were more likely to develop an alcohol use disorder (AUD) over the course of the study.

from Top Health News -- ScienceDaily https://ift.tt/35fIeBr

Researchers have identified a molecular 'address' that explains how the cancer-related protein PRC2 binds to RNA to silence genes. The study resolves a longstanding debate about the contradictory behavior between PRC2 and RNA. The findings could have important implications for development of drugs to treat cancer and other diseases.

from Top Health News -- ScienceDaily https://ift.tt/2XaV7YW

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