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Researchers found that peristaltic pump flow mechanically breaks supersaturation to induce amyloid formation by hen egg white lysozyme, a-synuclein, amyloid b 1-40, and b2-microglobulin. The high shear stresses induced by peristaltic flow likely reflect those that occur the blood and cerebrospinal fluid, suggesting that this factor could promote amyloidosis.

from Top Health News -- ScienceDaily https://ift.tt/P6sO4Qx

The ability to make the connection between an event and its consequences -- experts use the term associative learning -- is a crucial skill for adapting to the environment. It has a huge impact on our mental health. A study shows that children of primary school age demonstrate the highest learning performance in this area. The results pave the way for a fresh perspective on associative learning disorders, which are linked to the development of mental illness later in life.

from Top Health News -- ScienceDaily https://ift.tt/G7raHRW

New findings could help make immunotherapies for brain cancer more effective. The team analyzed almost 200,000 individual immune cells in tumor samples taken from patients with glioma, the most common and aggressive type of primary brain cancer. The researchers describe four gene expression 'programs' -- sets of genes with coordinated activity -- that either suppress the immune system or make it more active. Defining and understanding what drives these programs could one day help researchers target them with new drugs to dial up or down specific parts of the immune system to improve patient response to immunotherapy.

from Top Health News -- ScienceDaily https://ift.tt/Dc1LAzq

Imagine a future where the grip of cocaine use disorder can be loosened, where cravings fade, and the risk of relapse diminishes. A new study brings this vision closer to reality. The research has identified a critical brain circuit that plays a pivotal role in regulating cocaine-seeking behavior.

from Top Health News -- ScienceDaily https://ift.tt/MDP3YTU

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