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When pain signals are passed along the nervous system, proteins called calcium channels play a key role. Researchers have now pinpointed the exact location of a specific calcium channel fine-tuning the strength of pain signals. This knowledge can be used to develop drugs for chronic pain that are more effective and have fewer side effects.

from Top Health News -- ScienceDaily https://ift.tt/JKOMykx

Researchers have used machine learning and supercomputer simulations to investigate how tiny gold nanoparticles bind to blood proteins. The studies discovered that favorable nanoparticle-protein interactions can be predicted from machine learning models that are trained from atom-scale molecular dynamics simulations. The new methodology opens ways to simulate efficacy of gold nanoparticles as targeted drug delivery systems in precision nanomedicine.

from Top Health News -- ScienceDaily https://ift.tt/L85vXWe

A randomized, phase 2 clinical trial shows that adding high-dose, intravenous (IV) vitamin C to chemotherapy doubles the overall survival of patients with late-stage metastatic pancreatic cancer from eight months to 16 months. The finding adds to mounting evidence of the benefits of high-dose, IV vitamin C in treating cancer.

from Top Health News -- ScienceDaily https://ift.tt/iLq47xb

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