Health & Fitness

A concerning increase in global rates of severe invasive infections becoming resistant to key antibiotics has a team of infectious disease researchers studying a recently emerged strain of bacteria called Streptococcus dysgalactiae subspecies equisimilis. These infections range in severity from strep throat to flesh-eating disease.

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Artificial intelligence (AI) can provide same-day assessments of antimicrobial resistance for patients in intensive care -- critical to preventing life-threatening sepsis.

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Patients with Huntington's disease have a genetic mutation that triggers proteins to misfold and clump together in the brain. These clumps interfere with cell function and eventually lead to cell death. The new treatment leverages peptide-brush polymers, which act as a shield to prevent proteins from binding to one another. In studies in mice, the treatment successfully rescued neurons to reverse symptoms.

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A team has developed a large-scale drug screening technique that can track target molecule behavior within cells. The researchers verified their technique by testing the epidermal growth factor receptor (EGFR), a known target for cancer drugs. Their drug screening resulted in the identification of the known drugs, as well as others that were not previously known to affect EGFR. This new method can potentially help develop new drugs and repurpose existing drugs.

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Scientists have developed a new method of genetic analysis, which extracts more precise data than previously used methods when looking at DNA, and will improve our understanding of the genetic basis of rare and complex diseases. The findings explain a new method of analyzing genetics, which determines the extent to which genes are involved in phenotype formation. The previously used method extracted information using averages from different datasets, meaning that it had limitations in terms of the type of information it could provide, and what scientists could learn from it.

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People with stronger autistic trails showed distinct exploration patterns and higher levels of persistence in a computer game, ultimately resulting in better performance than people with lower scores of autistic traits, according to a new study.

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With its emphasis on opioid overdose prevention, the first guideline for primary care providers from the American Academy of Pediatrics on prescribing opioids for acute pain in children and adolescents extends beyond responsible pain management.

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