Health & Fitness

Heliozoan axopodia are important for their motility. However, the underlying mechanism of their axopodial contraction has remained ambiguous. Recently, researchers have reported that microtubules are simultaneously cleaved at multiple sites, allowing the radiating axopodia in a heliozoan, Raphidocystis contractilis, to disappear almost instantly. They have now identified the gene set and proteins involved in this microtubule disruption. This research can help develop a method to detect water pollution and evaluate the efficacy of new anticancer drugs.

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Patients hospitalized with fractures typically receive an injectable blood thinner, low-molecular-weight heparin, to prevent life-threatening blood clots. A new clinical trial, however, found that inexpensive over-the-counter aspirin is just as effective.

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An investigational HIV vaccine regimen tested among men who have sex with men (MSM) and transgender people was safe but did not provide protection against HIV acquisition, an independent data and safety monitoring board (DSMB) has determined. The HPX3002/HVTN 706, or 'Mosaico,' Phase 3 clinical trial began in 2019 and involved 3,900 volunteers ages 18 to 60 years in Europe, North America and South America. Based on the DSMB's recommendation, the study will be discontinued.

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In a study of patients with a history of facial keratinocyte carcinoma, 20.9% of those treated with nonablative fractional lasers experienced a subsequent keratinocyte carcinoma, compared with 40.4% of patients who did not receive laser treatment.

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The earlier infants begin to taste small samples of solid food, the earlier they eat more food and stop breastfeeding. This is shown in a new study, in which the mothers of 1,251 infants from all over Sweden participated. Almost half of the infants received tastings at the age of four months.

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Timing from first meal to last meal was not associated with weight loss in a six-year study: Eating less overall and fewer large meals may be a more effective weight management strategy than restricting meals to a narrow time window, such as intermittent fasting, according to a study that analyzed the electronic health records of about 550 adults who were followed for six years. The time interval from first to last meal was not associated with weight change during the six-year study.

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Regulatory mechanisms of nutrient-dependent neuronal development can be explored at the molecular level with the Drosophila C4da neuron located in the fruit flies' larvae. The hyperarborization phenotype was not caused by low concentrations of amino acids but rather by a simultaneous deficiency in vitamins, metal ions, and cholesterol. Nutrient-dependent development of somatosensory neurons plays a role in optimizing a trade-off between searching for high-nutrient foods and escaping from noxious environmental threats.

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