Health & Fitness

Scientists reported on an experimental gene-therapy-like technique to restore the normal activity of the TCCF4 gene deficient in individuals with Pitt-Hopkins syndrome.

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It's always rewarding when what started out as largely an academic endeavor turns out to impact a lot of people -- in this case women. Women suffering from endometriosis, polycystic ovary syndrome (PCOS) and preeclampsia may be protected from future heart disease if they carry a specific common genetic variant on the surface of cells (insulin-like growth factor-1 receptor, or IGF1R). The research suggests new options for personalized screening and surveillance for cardiovascular disease.

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Immunotherapy unleashes the power of the immune system to fight cancer. However, for some patients, immunotherapy doesn't work, and new research may help explain why. When immune cells called T lymphocytes infiltrate malignant tumors, the genetic program of those T cells and the developmental path they then follow, may affect their response to immunotherapy and predict overall patient survival, according to a new study. The results overturn the prevailing model of immune responses in melanoma and present different therapeutic approaches.

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Researchers have identified rare genetic markers in M. tuberculosis that could improve early detection of drug-resistant strains of the disease, helping prevent their spread.

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To provide a convenient tool for the early detection of injuries, researchers have developed a portable MRI device for diagnosing cartilage damage in the wrist. Using this device, the researchers imaged the wrists of tennis players at a tennis school. Several athletes were found to have cartilage damage without any other symptoms of an injury. Thus, this device provides a convenient early screening tool to help prevent further injury or damage.

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Young adults who were at risk of food insecurity had increased incidence of diabetes 10 years later, according to a new study. While previous research has associated food insecurity with a range of health issues including diabetes, obesity and hypertension, this study showed a connection over time, suggesting a causal relationship. Researchers analyzed data on nearly 4,000 people from the National Longitudinal Study of Adolescent to Adult Health. They found that adults ages 24-32 who said they'd been worried about food running out in the last year showed greater incidence of diabetes, either through blood glucose tests or self-reports, at ages 32-42, compared to those who did not report food insecurity risk.

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People don't want science anywhere near their delicious chocolate chip cookies. But they're happy to have science create body wash that fights odor-causing bacteria.

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