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Acute myeloid leukemia (AML) is a cancer of white blood cells. Researchers discovered that AML cancer cells depend on a protein called SCP4 to survive. They think the previously little-known protein is involved in a metabolic pathway the cancer cells need to survive. SCP4 provides researchers with a potential new therapeutic approach for this aggressive cancer.

from Top Health News -- ScienceDaily https://ift.tt/3zVOso3

A new study reveals important insights into the molecular mechanisms that underpin the body's natural defences against the development of skin cancer. The protein CSDE1 coordinates a complex chain of events that enable senescence in skin cells. The senescent cells act as a firewall against cancer, suppressing the formation of tumours. The findings are surprising because CSDE1 has been previously linked to driving the formation of cancers. The results offer new clues into the behavior of skin cancer at the cellular level, paving the way for potential new therapeutic targets to treat the disease.

from Top Health News -- ScienceDaily https://ift.tt/3HVRHyF

To understand how cranial neural crest cells (CNCCs) help form many more body parts than the skull and facial skeleton, scientists from the lab of Gage Crump created a series of atlases over time to understand the molecular decisions by which CNCCs commit to forming specific tissues in developing zebrafish. The researchers labeled and tracked CNCCs throughout the lifetime of zebrafish. With the help of a new computational analysis they created, they identified genetic signs that point to the specific tissues CNCCs were destined to form. The researchers also identified many of the potential switches that allow CNCCs to form these very different cell types.

from Top Health News -- ScienceDaily https://ift.tt/3zMdfeo

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