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As a psychiatric disorder with onset in adulthood, schizophrenia is thought to be triggered by some combination of environmental factors and genetics, although the exact cause is still not fully understood. Researchers have now found a correlation between schizophrenia and somatic copy-number variants, a type of mutation that occurs early in development but after genetic material is inherited. This study is one of the first to rigorously describe the relationship between somatic -- not inherited -- genetic mutations and schizophrenia risk.

from Top Health News -- ScienceDaily https://ift.tt/d5Kpm0q

Osteoarthritis is the most common degenerative joint disease, affecting 22% of adults over 40 globally. Although the condition has been extensively studied through a medical perspective, the molecular changes associated with osteoarthritis remain unclear. In a new study, researchers have used a combination of techniques to track the progression of the disease and the changes associated with it.

from Top Health News -- ScienceDaily https://ift.tt/TYolQOA

Kenyan patients who spend more than three days in the nation's hospitals are more likely to harbor a form of bacteria resistant to one of the most widely used antibiotic classes, according to a recent study. The research team found that 66% of hospitalized patients were colonized with bacteria resistant to third-generation cephalosporins, compared to 49% among community residents. Third-generation cephalosporins are typically used for serious infections, and resistance to these antibiotics leaves limited options for treating patients with some bacterial infections. The study was part of a pair of projects in Kenya and a third in Guatemala to determine the prevalence of antibiotic-resistant bacteria. The research also aimed to identify risk factors for colonization with bacteria resistant to important and frequently used classes of antibiotics, including third-generation cephalosporins.

from Top Health News -- ScienceDaily https://ift.tt/qxlZQ7F

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