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December 2023

Laura Hill is an avid runner but knows that time out from exercise can make you feel like you're on the back foot. Here's how to get moving again, in a way that won't overwhelm the body, but will build its strength. 

from Health | body+soul https://www.bodyandsoul.com.au/fitness/5-ways-to-get-back-into-exercise-from-people-whove-taken-a-break-too/news-story/0edbfb31671a5e112db7db6196af7c23

Researchers have leveraged a complex web of data to test a hypothesis: That structural racism is associated with resources and structures at the neighborhood level that are closely associated with poor health. What they found in an analysis of highly localized, community level data illustrates how racism is deeply interrelated with poor health outcomes.

from Top Health News -- ScienceDaily https://ift.tt/xDpB4lb

A new study has demonstrate that the ingestion of two of the most commercially available algal species are rich in protein which supports muscle remodeling in young healthy adults. Their findings suggest that algae may be an interesting and sustainable alternative to animal-derived protein with respect to maintaining and building muscle.

from Top Health News -- ScienceDaily https://ift.tt/Ch0ia52

The intricate process of duplicating genetic information, referred to as DNA replication, lies at the heart of the transmission of life from one cell to another and from one organism to the next. This happens by not just simply copying the genetic information; a well-orchestrated sequence of molecular events has to happen at the right time. Scientists have recently uncovered a fascinating aspect of this process known as 'replication timing' (RT) and how special this is when life commences.

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Researchers have comprehensively identified the allosteric control sites found in the protein KRAS. These are highly sought after targets for drug development, representing secret vulnerabilities which can be exploited to control the effects of one of the most important causes of cancer. The study presents the first complete control map for any protein and is expected to greatly accelerate the discovery of safer, more effective cancer treatments.

from Top Health News -- ScienceDaily https://ift.tt/gRIWJqu

An interdisciplinary team consisting of researchers has revealed a striking similarity between the memory processing of artificial intelligence (AI) models and the hippocampus of the human brain. This new finding provides a novel perspective on memory consolidation, which is a process that transforms short-term memories into long-term ones, in AI systems.

from Top Health News -- ScienceDaily https://ift.tt/hiPnyWe

Researchers successfully tested a simple intervention that could unlock greater anti-tumor power in therapies that use T cells -- an approach known as 'cell-based therapy,' which uses specially designed T cells to fight cancer. The team has proven an exciting concept: that the common cholesterol drug fenofibrate can boost T cells' ability to destroy human tumors.

from Top Health News -- ScienceDaily https://ift.tt/MUpaEAJ

A type of cell that plays a crucial role in tissue repair after a heart attack may also inadvertently be why cutting-edge cell therapies cause an increased risk of rhythm disorders, according to a new study. Researchers hope the findings could open up new pathways to safe regenerative treatments for people who have suffered a heart attack. 

from Top Health News -- ScienceDaily https://ift.tt/z7mY46G

Researchers have discovered that a certain kind of protein similar to hemoglobin, called cytoglobin, plays an important role in the development of the heart. Specifically, it affects the correct left-right pattern of the heart and other asymmetric organs. The findings could eventually lead to the development of new therapeutic interventions to alter the processes that lead to these defects.

from Top Health News -- ScienceDaily https://ift.tt/o7flNqs

Artificial Intelligence (AI) and 3D images of the human tongue have revealed that the surface of our tongues are unique to each of us, new findings suggest. The results offer an unprecedented insight into the biological make-up of our tongue's surface and how our sense of taste and touch differ from person to person.

from Top Health News -- ScienceDaily https://ift.tt/SlTy1tU

New research reveals that neurons in the preoptic hypothalamus -- the region of the brain that regulates sleep and body temperature -- are rhythmically activated during non-rapid eye movement sleep (NREM). Stress activates these brain cells out of turn, causing 'microarousals,' that interrupt sleep cycles and decrease the duration of sleep episodes, according to new research.

from Top Health News -- ScienceDaily https://ift.tt/ew6O97h

A new scientific method holds importance in the creation of customized medicine aimed at precisely targeting diseased cells, representing a pivotal stride towards more efficient and gentle treatments to optimize patients' quality of life. The novel method has been developed to enhance the synthesis of therapeutic oligonucleotides for targeted drugs.

from Top Health News -- ScienceDaily https://ift.tt/WjGREK9

By monitoring changes in circulating tumor DNA (ctDNA) among 30 patients treated with immunotherapies for metastatic non-small cell lung cancers, researchers were able to determine molecular response -- the clearance of tumor genetic material in the bloodstream.

from Top Health News -- ScienceDaily https://ift.tt/LX3vjbR

Glioblastoma is one of the most treatment-resistant cancers, with those diagnosed surviving for less than two years. In a new study, researchers have found that a largely understudied cell could offer new insight into how the aggressive, primary brain cancer is able to resist immunotherapy.

from Top Health News -- ScienceDaily https://ift.tt/J3xOqg5

Medical researchers found a way to grow samples of different types of neuroendocrine tumors (NETs) in the lab. While generating their new model, the researchers discovered that some pulmonary NETs need the protein EGF to be able to grow. These types of tumors may therefore be treatable using inhibitors of the EGF receptor.

from Top Health News -- ScienceDaily https://ift.tt/WqKfPmd

A research team has focused on generative AI as an information-gathering tool in the medical field. The results showed that one of the generative AIs suggested mostly fictitious references, while the other suggested multiple references with the same level of accuracy as the researchers. It is advised to use different generative AIs depending on the type of information needed.

from Top Health News -- ScienceDaily https://ift.tt/PW196Tt

Post-surgery pain relief has shifted away from opioid-containing medications over the past seven years, but the downward trend has slowed since 2020, a new study shows. Overall, the rate of surgery-related opioid prescriptions dropped by 36% from 2016 to the end of 2022, and the average amount of opioids in those prescriptions dropped by 46%.

from Top Health News -- ScienceDaily https://ift.tt/j0ymMbD

After more than a decade of developing fluorescent probes, a research team has now released the culmination of their years of work: A comprehensive collection of rhodamine-based dyes, the novel chemistry they developed to synthesize them and insights that provide a roadmap for designing future probes.

from Top Health News -- ScienceDaily https://ift.tt/Xt1kBSL

The complexity of living organisms is encoded within their genes, but where do these genes come from? Researchers resolved outstanding questions regarding the origin of small regulatory genes, and described a mechanism that creates their DNA palindromes. Under suitable circumstances, these palindromes evolve into microRNA genes.

from Top Health News -- ScienceDaily https://ift.tt/Wm0Bslo

A new method can identify unique immune cell receptors and their location in tissue, a new study reports. The researchers predict that the method will improve the ability to identify which immune cells contribute to disease processes and open up opportunities to develop novel therapies for numerous diseases.

from Top Health News -- ScienceDaily https://ift.tt/8RQTtpG

Despite the Roman Empire's extensive military and cultural influence on the nearby Balkan peninsula, a DNA analysis of individuals who lived in the region between 1 and 1000 CE found no genetic evidence of Iron Age Italian ancestry. Instead, a new study has revealed successive waves of migrations from Western Anatolia, central and northern Europe, and the Pontic-Kazakh Steppe during the Empire's reign.

from Top Health News -- ScienceDaily https://ift.tt/s14fSYp

Engineers have developed a bio-compatible ink that solidifies into different 3D shapes and structures by absorbing ultrasound waves. Because the material responds to sound waves rather than light, the ink can be used in deep tissues for biomedical purposes ranging from bone healing to heart valve repair.

from Top Health News -- ScienceDaily https://ift.tt/pDBOzLY

Researchers have discovered that misreading of therapeutic mRNAs by the cell's decoding machinery can cause an unintended immune response in the body. They have identified the sequence within the mRNA that causes this to occur and found a way to prevent 'off-target' immune responses to enable the safer design of future mRNA therapeutics.

from Top Health News -- ScienceDaily https://ift.tt/bW1yuYX

3D eye scans can reveal vital clues about kidney health that could help to track the progression of disease, research suggests. The advance could revolutionize monitoring of kidney disease, which often progresses without symptoms in the early stages. Experts say the technology has potential to support early diagnosis as current screening tests cannot detect the condition until half of the kidney function has been lost.

from Top Health News -- ScienceDaily https://ift.tt/HWpnmMi

Seeing robots made with soft, flexible parts in action appears to lower people's anxiety about working with them or even being replaced by them. A study found that watching videos of a soft robot working with a person at picking and placing tasks lowered the viewers' safety concerns and feelings of job insecurity. This was true even when the soft robot was shown working in close proximity to the person. This finding shows soft robots hold a potential psychological advantage over rigid robots made of metal or other hard materials.

from Top Health News -- ScienceDaily https://ift.tt/YVhciX0

For the first time, researchers have mapped the financial sector's influence on the emergence of infectious diseases. They find that a relatively small number of powerful financial institutions, such as investment companies, pension funds, and banks could help accelerate actions that mitigate the risks of new pandemics, according to a new study.

from Top Health News -- ScienceDaily https://ift.tt/W5RPsIQ

Kidney stones affect nearly 10% of the global population. For more than three decades, thiazide diuretics, a common medication used for high blood pressure, have been the standard of care for kidney stone prevention because they reduce the excretion of urinary calcium.  

from Top Health News -- ScienceDaily https://ift.tt/b1LZ8iQ

In a world grappling with deep-seated division and social upheaval, empathy has become more critical than ever. But science suggests when it comes to evoking empathy, our imagination is more powerful than we previously thought. A new study reveals how the different ways to experience empathy affect our willingness to help others.

from Top Health News -- ScienceDaily https://ift.tt/EjQSBiC

Researchers have uncovered that tinnitus, an incurable persistent ringing or other sounds in the ears, might result from underlying auditory nerve damage that can't be detected on conventional hearing tests. The work builds upon previous research into cochlear synaptopathy or 'hidden hearing loss,' a difficulty hearing in noisy environments despite showing normal results on hearing tests. The researchers hope these new findings into the mechanisms underlying tinnitus could lead to treatment options. 

from Top Health News -- ScienceDaily https://ift.tt/17hwQAl

Researchers have developed a new modeling approach to assess the likelihood of human survivability and liveability during exposure to extreme heat. The new model can be applied in any climate regime and customized with populations that have potential co-morbidities. The approach integrates well-established principles from thermal physiology and human biophysics. The study's results include current and future extreme heat across very hot and dry, and very hot and humid conditions, with risks increasing over most of the world.

from Top Health News -- ScienceDaily https://ift.tt/g2KDneN

Researchers have developed a new experiment to better understand what people view as moral and immoral decisions related to driving vehicles, with the goal of collecting data to train autonomous vehicles how to make 'good' decisions. The work is designed to capture a more realistic array of moral challenges in traffic than the widely discussed life-and-death scenario inspired by the so-called 'trolley problem.'

from Top Health News -- ScienceDaily https://ift.tt/bcOML48

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