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March 2025

Most haptic devices only deliver feedback as simple vibrations. New device applies dynamic forces in any direction to simulate a more realistic sense of touch. Small, lightweight device can enhance virtual reality, help individuals with visual impairments, provide tactile feedback for remote health visits and more.

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The reuse of human urine would allow for the production of sustainable fertilizers for urban agriculture, with significant environmental benefits, a new study concludes. The research evaluates the environmental impact of nitrogen recovery from the yellow waters of buildings. In addition to promoting sustainable agriculture, it would reduce carbon dioxide emissions and water consumption.

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Compared with those who spent most of their time in a single room, people with heart failure with preserved ejection fraction (HFpEF) who were able to travel outside of their home without assistance were significantly less likely to be hospitalized or die within a year, according to a new study. The findings underscore the value of supporting holistic care and encouraging people with heart failure to maintain an active lifestyle and engage with others in their community to the extent possible, researchers said.

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Researchers have found a unique molecular signature and genes in the orbitofrontal cortex associated with heroin-seeking behavior. A preclinical rodent model implicated a gene called Shisa7 as the key predictor. A new study provides valuable insights into the neurobiological mechanisms underlying heroin addiction and may have implications for the development of innovative strategies to combat the ongoing opioid epidemic.

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Stroke survivors who have attended some level of higher education may face even steeper mental declines, according to a study. The findings suggest that attending higher education may enable people to retain greater cognitive ability until a critical threshold of brain injury is reached after a stroke.

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People with autism are typically diagnosed by clinical observation and assessment. To deconstruct the clinical decision process, which is often subjective and difficult to describe, researchers used a large language model (LLM) to synthesize the behaviors and observations that are most indicative of an autism diagnosis. Their results show that repetitive behaviors, special interests, and perception-based behaviors are most associated with an autism diagnosis. These findings have potential to improve diagnostic guidelines for autism by decreasing the focus on social factors -- which the established guidelines in the DSM-5 focus on but the model did not classify among the most relevant in diagnosing autism.

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A study found that when people were told to imagine their virtual bodies in pain, their brains resisted the illusion of ownership. Their findings could provide insights into why some people may struggle with feeling connected to their own bodies, particularly in contexts involving depersonalization or negative physical states.

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Our blood consists of many cell types that develop through different stages from a precursor type -- the blood stem cell. An international research team has now investigated the developmental pathways of blood cells in humans. The results yielded a surprise: Even stem cells possess surface proteins that enable them to suppress the activation of inflammatory and immune responses in the body. This finding is particularly relevant for stem cell transplants, applied for the treatment of e.g. leukemia.

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Aging compromises the lymphatic vessels surrounding the brain, disabling waste drainage from the brain and impacting cognitive function. Researchers boosted lymphatic vessel integrity in old mice and found improvements in their memory compared with old mice without rejuvenated lymphatic vessels.

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A study has found that a single dose of the Imvanex vaccine provides protection against Mpox with 84% effectiveness. For people with HIV, however, a single dose of the vaccine fails to offer sufficient protection. All at-risk groups, and people with HIV in particular, should therefore receive the second dose of the vaccine as recommended.

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Campylobacter infections are the most common foodborne illnesses in the U.S., sickening an estimated 1.5 million people each year. A new study examined records of Campylobacter jejuni infections from 10 states, plotting regional, age-related, and drug-resistance trends from 2013 to 2019. The study found that drug-resistant C. jejuni infections were highest in the 20-39 age group and that quinolone-resistant C. jejuni infections increased from 2013-2019. The researchers also identified regional differences in C. jejuni resistance to quinolones and six other classes of antibiotics.

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The smart MAIJU jumpsuit offers a novel approach to at-home monitoring of infants' early motor development. The wearable device combines expertise in medicine, measuring technology and AI, enabling objective and accurate assessment of children's motor skills without the presence of researchers.

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Brain implants hold immense promise for restoring function in patients with paralysis, epilepsy and other neurological disorders. But a team of researchers has discovered that bacteria can invade the brain after a medical device is implanted, contributing to inflammation and reducing the device's long-term effectiveness.

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Until now, a global evaluation of ocean current energy with actual data was lacking. Using 30 years of NOAA's Global Drifter Program data, a study shows that ocean currents off Florida's East Coast and South Africa have exceptionally high-power densities, ideal for electricity generation. With densities over 2,500 watts per square meter, these regions are 2.5 times more energy-dense than 'excellent' wind resources. Shallow waters further enhance the potential for ocean current turbines, unlike areas like Japan and South America, which have lower densities at similar depths.

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Early-life adversity affects more than half of the world's children and is a significant risk factor for cognitive and mental health problems later in life. In an extensive and up-to-the-minute review of research in this domain, scholars illuminate the profound impacts of these adverse childhood experiences on brain development and introduce new paths for understanding and tackling them.

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It has long been thought that only nerve and heart cells use electric impulses to communicate, while epithelial cells -- which compose the linings of our skin, organs and body cavities -- are mute, serving mostly as protective barriers that can absorb and secrete various substances. But researchers have now upended the status quo by showing that epithelial cells do indeed 'talk' to each other, albeit with slow electrical signals.

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Struggling to afford food today could mean heart problems tomorrow. Young adults experiencing food insecurity have a 41% greater risk of developing heart disease in midlife, even after accounting for demographic and socioeconomic factors, according to a new study. Food insecurity -- struggling to get enough nutritious food to stay healthy -- affects one in eight households in the U.S. each year.

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Until now, doctors knew hepatic stellate cells mainly as drivers of liver fibrosis. The actual functions of this cell type have hardly been studied to date. Researchers have now determined that hepatic stellate cells control liver metabolism as well as liver regeneration and size. The results of the study could contribute to new therapeutic approaches for liver diseases.

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A new study suggests a promising alternative to previous attempts to remove the sticky, toxic amyloid beta plaques from brains with Alzheimer's Disease: enhancing the brain's own immune cells to clear these plaques more effectively. The findings could reshape the future of Alzheimer's treatments, shifting the focus from simply removing plaques to harnessing the brain's natural defenses.

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Technology is changing how physicians think about assessing patients and, in turn, how patients expect to be able to measure their own health. Apps designed for smartphones and wearable devices can provide unique insights into users' brain health. It is estimated that 55 million individuals worldwide suffer from some form of dementia. Alzheimer's disease and related dementias being the leading causes, with numbers expected to triple by 2050.

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Researchers have created washable and durable magnetic field sensing electronic textiles -- thought to be the first of their kind -- which they say paves the way to transform use in clothing. This technology will allow users to interact with everyday textiles or specialized clothing by simply pointing their finger above a sensor.

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Injuries to the articular cartilage in different joints, including the knee, are painful and limit mobility. Therefore, researchers are developing cartilage implants using cells from the patient's nasal septum. A recent study shows that giving these cartilage implants more time to mature significantly improved clinical efficacy, even in patients with complex cartilage injuries. This suggests that the method could also be suitable for the treatment of degenerated cartilage in osteoarthritis.

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The neurotransmitter glutamate is essential for regulating everything from mood to memory, but it can also encourage a toxic buildup of protein, which can contribute to Alzheimer's and related diseases. Scientists now describe a new approach for counteracting these devastating and often fatal neurodegenerative effects. Researchers made their discovery by studying lab mice as well as human brain 'organoids,' which are rudimentary brain-like structures grown in the lab.

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A new study has unveiled a precise picture of how an ion channel found in most mammalian cells regulates its own function with a 'ball-and-chain' channel-plugging mechanism. The findings boost the understanding of ion channel biology and could lead to new drugs that target these channels to treat disorders such as epilepsy and hypertension.

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A new study that has the potential to change the landscape of hepatitis B transmission in Africa. Researchers conducted an analysis revealing key interventions that could effectively eliminate vertical transmission of chronic hepatitis B, one of the leading causes of liver cancer and cirrhosis in the region.

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Research reveals how a specific mutation in a protein called TRAF1 can shut down an overactive immune response, dramatically reducing inflammation in mice. This discovery could pave the way for a new class of drugs to treat rheumatoid arthritis, according to one of the authors. Using gene-editing technology, the researchers identified a critical mutation of a protein called TRAF1 and discovered that this mutation dramatically reduces inflammation by disrupting a critical molecular interaction that fuels the immune system into kicking into overdrive.

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