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February 2024

When people lack visual imagination, this is known as aphantasia. Researchers investigated how the lack of mental imagery affects long-term memory. They were able to show that changes in two important brain regions, the hippocampus and the occipital lobe, as well as their interaction, have an influence on the impaired recall of personal memories in aphantasia.

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Iron is a micronutrient for plants. Biologists from the Institute of Botany at Heinrich Heine University D sseldorf (HHU) describe in a study, which has now been published in the Journal of Cell Biology, that regulatory proteins for iron uptake behave particularly dynamically in the cell nucleus when the cells are exposed to blue light -- an important signal for plant growth. They found that the initially homogeneously distributed proteins relocated together into 'biomolecular condensates' in the cell nucleus shortly after this exposure.

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A report from the world's leading scientific and medical experts on hormone-related health conditions raises new concerns about the profound threats to human health from endocrine disrupting chemicals (EDCs) that are ubiquitous in our surroundings and everyday lives. Everyday exposures to EDCs in the environment may be linked to increasing rates of infertility, diabetes, immune deficiencies, and other serious conditions; Highly Hazardous Pesticides pose ongoing threats.

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The idea that people make decisions based on social context is not a new one in neural economic games. But now, for the first time, researchers show the impact of the social context may spring from the dynamic interactions of dopamine and serotonin. Researchers built carbon-fiber electrodes that were implanted in patients receiving Deep Brain Stimulation surgery. The method allows researchers to measure more than one neurotransmitter at a time, revealing a dance that has never been seen before.

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Researchers have investigated whether the body is truly disconnected from the external world during sleep. To do so, they focused on how heartbeat changes when we hear different words during sleep. They found that relaxing words slowed down cardiac activity as a reflection of deeper sleep and in comparison to neutral words that did not have such a slowing effect. This discovery sheds new light on brain-heart interactions during sleep.

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New research used brain scanning technology to understand the effect of advertisements that try to sell products with talking versions of themselves. The work suggests that that anthromorphic displays lead to different cognition, and that buyers are likely to spend up to 20 percent more on more complex products promoted in advertisements that anthropomorphizes the product.

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People with higher exposure to traffic-related air pollution were more likely to have high amounts of amyloid plaques in their brains associated with Alzheimer's disease after death, according to a new study. Researchers looked at fine particulate matter, PM2.5, which consists of pollutant particles of less than 2.5 microns in diameter suspended in air.

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The iconic baleen whales, such as the blue, gray and humpback whale, depend on sound for communication in the vast marine environment where they live. Now researchers have for the first time found that baleen whales evolved novel structures in their larynx to make their vast array of underwater songs.

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The drug finasteride, also known as Propecia or Proscar, treats male pattern baldness and enlarged prostate in millions of men worldwide. But a new study suggests the drug may also provide a surprising and life-saving benefit: lowering cholesterol and cutting the overall risk of cardiovascular disease.

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Book sharing is a popular way parents engage young children in conversation. However, not all parents are comfortable with book sharing and not all children like having books read to them. Research provides an alternative. To boost the quality of a preschooler's language experience and skills, consider reminiscing with them. Findings show reminiscing is very good at eliciting high quality speech from parents, and in many ways, is just as good as book sharing (wordless picture books).

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Traditional wearable thermal control devices use bulky and noisy components. New advancements such as the small electrohydrodynamic pump and soft tubes offer a promising avenue for such devices. However, they require real-time flow-rate monitoring, requiring additional equipment. Now, a team of researchers has developed a novel device that uses self-sensing technology for flow-rate monitoring, resulting in a compact personal thermal control device, marking a significant step in wearable device research.

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School uniforms could be restricting young people from being active, particularly primary school-aged girls, according to a new study. The study used data about the physical activity of more than a million five-to-17-year-olds in 135 countries. In countries where a majority of schools require students to wear uniforms, fewer young people are meeting the World Health Organization's recommendations for physical activity (60 minutes per day). Fewer girls are meeting the guidelines than boys -- with a standard gap of 7.6 percentage points between boys and girls.

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Researchers report that ancient viruses may be to thank for myelin -- and, by extension, our large, complex brains. The team found that a retrovirus-derived genetic element or 'retrotransposon' is essential for myelin production in mammals, amphibians, and fish. The gene sequence, which they dubbed 'RetroMyelin,' is likely a result of ancient viral infection, and comparisons of RetroMyelin in mammals, amphibians, and fish suggest that retroviral infection and genome-invasion events occurred separately in each of these groups.

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Women who receive an mRNA-based COVID-19 vaccination or booster during pregnancy can provide their infants with strong protection against symptomatic COVID-19 infection for at least six months after birth, according to a new study. These findings reinforce the importance of receiving both a COVID-19 vaccine and booster during pregnancy to ensure that infants are born with robust protection that lasts until they are old enough to be vaccinated.

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Babies playfully tease others as young as eight months of age. Since language is not required for this behavior, similar kinds of playful teasing might be present in non-human animals. Now cognitive biologists and primatologists have documented playful teasing in four species of great apes. Like joking behavior in humans, ape teasing is provocative, persistent, and includes elements of surprise and play. Because all four great ape species used playful teasing, it is likely that the prerequisites for humor evolved in the human lineage at least 13 million years ago.

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In many cancers, such as ovarian cancer, each round of chemotherapy kills the majority of cancer cells, while a small population of them survives through treatment. These cells are typically more resistant for the next cycle of therapy and can thus regrow to a deadly, treatment resistant tumor. Researchers wanted to know how this small population of surviving cells differs from the other more sensitive cells already before the treatment. To enable this cellular time travel, they developed ReSisTrace, a methodology that takes advantage of the similarity of sister cells to trace back pre-existing treatment resistance in cancer.

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An international study has used a computational biology tool that, by analyzing a multitude of biological data from multiple sclerosis patients ranging from genetic information to the whole organism, reveals the relationship between elements of different biological scales and improves our knowledge and the diagnosis of the disease.

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Daily exposure to chemicals used in the manufacture of plastic food containers and many cosmetics may be tied to nearly 56,600 preterm births in the U.S. in 2018, a new study shows. The resulting medical costs, the authors of the report say, were estimated to reach a minimum of $1.6 billion and as much as $8.1 billion over the lifetime of the children.

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Scientists discovered a pathway from mitochondrial DNA replication stress to immune system activation and inflammation, finding that endosomes responsible for disposing of dysfunctional mitochondrial DNA were leaking mitochondrial DNA into the cell and prompting the inflammatory immune response. The pathway provides new targets for therapeutics that disrupt inflammation during aging and disease.

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A new study provides the first concrete data showing that many of these excess deaths were indeed uncounted COVID-19 deaths. The study compared reported COVID-19 deaths to excess deaths due to non-COVID, natural causes, such as diseases and chronic illnesses, and found that increases in non-COVID excess deaths occurred at the same time or in the month prior to increases in reported COVID-19 deaths in most US counties.

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Scientists can now predict which single-letter changes to the DNA within our genomes will alter genetic instructions and disrupt development, leading to changes such as the growth of extra digits and hearts. Such knowledge opens the door to predictions of which enhancer variants underlie disease in order to harness the full potential of our genomes for better human health.

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